Update of P2Y receptor pharmacology: IUPHAR Review 27.

Humans Neurons Purinergic P2Y Receptor Agonists Purinergic P2Y Receptor Antagonists Receptors, G-Protein-Coupled Receptors, Purinergic P2Y1 Signal Transduction

Journal

British journal of pharmacology
ISSN: 1476-5381
Titre abrégé: Br J Pharmacol
Pays: England
ID NLM: 7502536

Informations de publication

Date de publication:
06 2020
Historique:
received: 12 08 2019
revised: 12 01 2020
accepted: 15 01 2020
pubmed: 11 2 2020
medline: 22 6 2021
entrez: 11 2 2020
Statut: ppublish

Résumé

Eight G protein-coupled P2Y receptor subtypes respond to extracellular adenine and uracil mononucleotides and dinucleotides. P2Y receptors belong to the δ group of rhodopsin-like GPCRs and contain two structurally distinct subfamilies: P2Y

Identifiants

DOI: 10.1111/bph.15005 PMID: 32037507 PMC: PMC7205808
pubmed: 32037507
doi: 10.1111/bph.15005
pmc: PMC7205808
doi:

Substances chimiques

Purinergic P2Y Receptor Agonists 0
Purinergic P2Y Receptor Antagonists 0
Receptors, G-Protein-Coupled 0
Receptors, Purinergic P2Y1 0

Types de publication

Journal Article Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2413-2433

Subventions

Organisme : German Research Foundation
ID : FOR2372
Pays : International
Organisme : Integrated Research and Treatment Center (IFB) AdiposityDiseases (BMBF)
Pays : International
Organisme : Independent Research Fund Denmark
ID : DFF-4002-00162
Pays : International
Organisme : German Research Foundation
ID : SFB 1052
Pays : International
Organisme : German Research Foundation
ID : GRK1873
Pays : International
Organisme : Intramural NIH HHS
ID : ZIA DK031116
Pays : United States

Informations de copyright

© 2020 The British Pharmacological Society.

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Auteurs

Kenneth A Jacobson (KA)

Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, Massachusetts.
ORCID: 0000-0001-8104-1493

Esmerilda G Delicado (EG)

Dpto. Bioquimica y Biologia Molecular, Universidad Complutense de Madrid, Madrid, Spain.

Christian Gachet (C)

Université de Strasbourg INSERM, EFS Grand Est, BPPS UMR-S 1255, FMTS, Strasbourg, France.

Charles Kennedy (C)

Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
ORCID: 0000-0001-9661-5437

Ivar von Kügelgen (I)

Biomedical Research Center, Department of Pharmacology and Toxicology, University of Bonn, Bonn, Germany.

Beibei Li (B)

CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

M Teresa Miras-Portugal (MT)

Dpto. Bioquimica y Biologia Molecular, Universidad Complutense de Madrid, Madrid, Spain.

Ivana Novak (I)

Department of Biology, Section for Cell Biology and Physiology, University of Copenhagen, Copenhagen, Denmark.
ORCID: 0000-0002-8917-8010

Torsten Schöneberg (T)

Rudolf Schönheimer Institute of Biochemistry, Molecular Biochemistry, Medical Faculty, Leipzig University, Leipzig, Germany.

Raquel Perez-Sen (R)

Dpto. Bioquimica y Biologia Molecular, Universidad Complutense de Madrid, Madrid, Spain.

Doreen Thor (D)

Rudolf Schönheimer Institute of Biochemistry, Molecular Biochemistry, Medical Faculty, Leipzig University, Leipzig, Germany.
IFB AdiposityDiseases, Leipzig University Medical Center, Leipzig, Germany.
ORCID: 0000-0002-9522-5098

Beili Wu (B)

CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

Zhenlin Yang (Z)

CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

Christa E Müller (CE)

Pharmaceutical Institute, Department of Pharmaceutical and Medicinal Chemistry, University of Bonn, Bonn, Germany.
ORCID: 0000-0002-0013-6624

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Update of P2Y receptor pharmacology: IUPHAR Review 27.
questionsmedicales.fr › Cellules › Neurones › Update of P2Y receptor pharmacology: IUPHAR Review 27.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents purinergiques › Agonistes purinergiques › Agonistes des récepteurs purinergiques P2 › Agonistes des récepteurs purinergiques P2Y › Update of P2Y receptor pharmacology: IUPHAR Review 27.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents purinergiques › Antagonistes purinergiques › Antagonistes des récepteurs purinergiques P2 › Antagonistes des récepteurs purinergiques P2Y › Update of P2Y receptor pharmacology: IUPHAR Review 27.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs couplés aux protéines G › Update of P2Y receptor pharmacology: IUPHAR Review 27.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs purinergiques › Récepteurs purinergiques P2 › Récepteurs purinergiques P2Y › Récepteurs purinergiques P2Y1 › Update of P2Y receptor pharmacology: IUPHAR Review 27.
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Update of P2Y receptor pharmacology: IUPHAR Review 27.