Health-related quality of life among tonsillar carcinoma patients in Sweden in relation to treatment and comparison with quality of life among the population.


Journal

Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541

Informations de publication

Date de publication:
05 2020
Historique:
received: 03 08 2018
revised: 11 12 2019
accepted: 17 12 2019
pubmed: 11 2 2020
medline: 22 6 2021
entrez: 11 2 2020
Statut: ppublish

Résumé

The health-related quality of life (HRQOL) of tonsillar carcinoma survivors was explored to investigate any HRQOL differences associated with tumor stage and treatment. The survivors' HRQOL was also compared to reference scores from the population. In this exploratory cross-sectional study patients were invited 15 months after their diagnosis and asked to answer two quality of life questionnaires (EORTC QLQ- C30, EORTC QLQ- HN35), 405 participated. HRQOL was associated with gender, with males scoring better than females on a few scales. Patients' HRQOL was more associated with treatment than tumor stage. Patients' HRQOL was worse than that in an age- and sex-matched reference group from the normal population, the largest differences were found for problems with dry mouth followed by problems with sticky saliva, senses, swallowing and appetite loss. The tonsillar carcinoma patients had a worse HRQOL compared to the general population one year after treatment.

Sections du résumé

BACKGROUND
The health-related quality of life (HRQOL) of tonsillar carcinoma survivors was explored to investigate any HRQOL differences associated with tumor stage and treatment. The survivors' HRQOL was also compared to reference scores from the population.
METHODS
In this exploratory cross-sectional study patients were invited 15 months after their diagnosis and asked to answer two quality of life questionnaires (EORTC QLQ- C30, EORTC QLQ- HN35), 405 participated.
RESULTS
HRQOL was associated with gender, with males scoring better than females on a few scales. Patients' HRQOL was more associated with treatment than tumor stage. Patients' HRQOL was worse than that in an age- and sex-matched reference group from the normal population, the largest differences were found for problems with dry mouth followed by problems with sticky saliva, senses, swallowing and appetite loss.
CONCLUSIONS
The tonsillar carcinoma patients had a worse HRQOL compared to the general population one year after treatment.

Identifiants

pubmed: 32040223
doi: 10.1002/hed.26064
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

860-872

Informations de copyright

© 2020 Wiley Periodicals, Inc.

Références

2014-2018 [cited http://www.cancercentrum.se].
Infante-Cossio P, Torres-Carranza E, Cayuela A, Hens-Aumente E, Pastor-Gaitan P, Gutierrez-Perez JL. Impact of treatment on quality of life for oral and oropharyngeal carcinoma. Int J Oral Maxillofac Surg. 2009;38(10):1052-1058.
Shiboski CH, Schmidt BL, Jordan RC. Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20-44 years. Cancer. 2005;103(9):1843-1849.
Sload R, Silver N, Jawad BA, Gross ND. The role of Transoral robotic surgery in the management of HPV negative Oropharyngeal squamous cell carcinoma. Curr Oncol Rep. 2016;18(9):53.
Majchrzak E, Szybiak B, Wegner A, et al. Oral cavity and oropharyngeal squamous cell carcinoma in young adults: a review of the literature. Radiol Oncol. 2014;48(1):1-10.
L.H. Sobin MKG, Ch. Wittekind. TNM Classification of Malignant Tumours. Oxford, UK: Wiley and Blackwell; 2009.
Boscolo-Rizzo P, Pawlita M, Holzinger D. From HPV-positive towards HPV-driven oropharyngeal squamous cell carcinomas. Cancer Treat Rev. 2016;42:24-29.
Motz K, Chang HY, Quon H, Richmon J, Eisele DW, Gourin CG. Association of Transoral Robotic Surgery with Short-term and Long-term Outcomes and costs of Care in Oropharyngeal Cancer Surgery. JAMA Otolaryngol Head Neck Surg. 2017;143:580-588.
Bjordal K, Hammerlid E, Ahlner-Elmqvist M, et al. Quality of life in head and neck cancer patients: validation of the European Organization for Research and Treatment of cancer quality of life questionnaire-H&N35. J Clin Oncol. 1999;17(3):1008-1019.
Ringash J, Bezjak A. A structured review of quality of life instruments for head and neck cancer patients. Head Neck. 2001;23(3):201-213.
Hammerlid E, Bjordal K, Ahlner-Elmqvist M, et al. A prospective study of quality of life in head and neck cancer patients. Part I: at diagnosis. Laryngoscope. 2001;111(4 Pt 1):669-680.
Nordgren M, Jannert M, Boysen M, et al. Health-related quality of life in patients with pharyngeal carcinoma: a five-year follow-up. Head Neck. 2006;28(4):339-349.
Pourel N, Peiffert D, Lartigau E, Desandes E, Luporsi E, Conroy T. Quality of life in long-term survivors of oropharynx carcinoma. Int J Radiat Oncol Biol Phys. 2002;54(3):742-751.
Hammerlid E, Adnan A, Silander E. Population-based reference values for the European Organization for Research and Treatment of cancer head and neck module. Head Neck. 2017;39(10):2036-2047.
Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85(5):365-376.
Bjordal K, de Graeff A, Fayers PM, et al. A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. EORTC quality of life group. Eur J Cancer. 2000;36(14):1796-1807.
Ferris MJ, Zhong J, Switchenko JM, et al. Brainstem dose is associated with patient-reported acute fatigue in head and neck cancer radiation therapy. Radiother Oncol. 2018;126(1):100-106.
Station C, ed. 13.1 Sr. TX, USA: Stata Corp LP; 2016.
Osoba D, Rodrigues G, Myles J, Zee B, Pater J. Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol. 1998;16(1):139-144.
Cocks K, King MT, Velikova G, Fayers PM, Brown JM. Quality, interpretation and presentation of European Organisation for Research and Treatment of Cancer quality of life questionnaire core 30 data in randomised controlled trials. Eur J Cancer. 2008;44(13):1793-1798.
Abendstein H, Nordgren M, Boysen M, et al. Quality of life and head and neck cancer: a 5 year prospective study. Laryngoscope. 2005;115(12):2183-2192.
Michelson H, Bolund C, Nilsson B, Brandberg Y. Health-related quality of life measured by the EORTC QLQ-C30-reference values from a large sample of Swedish population. Acta Oncol. 2000;39(4):477-484.
Pierre CS, Dassonville O, Chamorey E, et al. Long-term quality of life and its predictive factors after oncologic surgery and microvascular reconstruction in patients with oral or oropharyngeal cancer. Eur Arch Oto-Rhino-Laryngol. 2014;271(4):801-807.
Oates J, Davies S, Roydhouse JK, Fethney J, White K. The effect of cancer stage and treatment modality on quality of life in oropharyngeal cancer. Laryngoscope. 2014;124(1):151-158.
Ling DC, Chapman BV, Kim J, et al. Oncologic outcomes and patient-reported quality of life in patients with oropharyngeal squamous cell carcinoma treated with definitive transoral robotic surgery versus definitive chemoradiation. Oral Oncol. 2016;61:41-46.
Broglie MA, Soltermann A, Haile SR, et al. Quality of life of oropharyngeal cancer patients with respect to treatment strategy and p16-positivity. Laryngoscope. 2013;123(1):164-170.
Ryzek DF, Mantsopoulos K, Kunzel J, et al. Early stage oropharyngeal carcinomas: comparing quality of life for different treatment modalities. Biomed Res Int. 2014;2014:421964.
Tschudi D, Stoeckli S, Schmid S. Quality of life after different treatment modalities for carcinoma of the oropharynx. Laryngoscope. 2003;113(11):1949-1954.
Martins SP, Ferreira CL, Del Giglio A. Placebo-controlled, double-blind, randomized study of a dry Guarana extract in patients with head and neck tumors undergoing Chemoradiotherapy: effects on fatigue and quality of life. J Dietary Suppl. 2017;14(1):32-41.
Endo K, Tsuji A, Kondo S, Wakisaka N, Murono S, Yoshizaki T. Carnitine is associated with fatigue following chemoradiotherapy for head and neck cancer. Acta Otolaryngol. 2015;135(8):846-852.
Schwarz R, Hinz A. Reference data for the quality of life questionnaire EORTC QLQ-C30 in the general German population. Eur J Cancer. 2001;37(11):1345-1351.
Hoxbroe Michaelsen S, Gronhoj C, Hoxbroe Michaelsen J, Friborg J, von Buchwald C. Quality of life in survivors of oropharyngeal cancer: a systematic review and meta-analysis of 1366 patients. Eur J Cancer. 2017;78:91-102.

Auteurs

Ali Adnan (A)

Department of Otorhinolaryngology-Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden.

Anders Högmo (A)

Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Hospital, Stockholm, Sweden.

Helena Sjödin (H)

Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Hospital, Stockholm, Sweden.

Maria Gebre-Medhin (M)

Department of Oncology and Radiation Physics, Skåne University Hospital, Lund University, Lund, Sweden.

Göran Laurell (G)

Department of Surgical Sciences, Section of Otorhinolaryngology and Head & Neck Surgery, Uppsala University, Uppsala, Sweden.

Johan Reizenstein (J)

Department of Oncology, Örebro University Hospital and Örebro University, Sweden.

Lovisa Farnebo (L)

Division of Otorhinolaryngology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.

Lena S Norberg (LS)

Department of Clinical Sciences/ENT, Umeå University, Umeå, Sweden.

Isak Notstam (I)

Department of Clinical Sciences/ENT, Umeå University, Umeå, Sweden.

Erik Holmberg (E)

Regional Cancer Center Western Sweden, Sahlgrenska University Hospital, Gothenburg, Sweden.

Hedda H Cange (HH)

Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden.

Eva Hammerlid (E)

Department of Otorhinolaryngology-Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH