[Botulism: A case report and literature review].

Botulisme : à propos d’un cas et revue de la littérature.
Anticholinergic toxidrome Botulism Botulisme Clostridium botulinum Neurotoxin Neurotoxine Oculomotor paralysis Paralysie oculomotrice Syndrome anticholinergique

Journal

La Revue de medecine interne
ISSN: 1768-3122
Titre abrégé: Rev Med Interne
Pays: France
ID NLM: 8101383

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 02 12 2019
revised: 07 01 2020
accepted: 24 01 2020
pubmed: 18 2 2020
medline: 17 12 2020
entrez: 17 2 2020
Statut: ppublish

Résumé

Botulism is a rare syndrome resulting from the action of a neurotoxin produced by Clostridium botulinum, that it is potentially life threatening if diagnosis is delayed. We report a 26-year-old woman who presented an acute onset of bilateral cranial neuropathies associated with an anticholinergic syndrome in the absence fever leading to consider and confirm the diagnosis of botulism. At the end of follow-up, 7 weeks later, the outcome was favorable with an almost complete neurologic recovery. Although botulism is uncommon, better awareness of its manifestations and high clinical suspicion should shorten diagnostic delay that makes the use of specific antitoxin ineffective. An acute onset of a bilateral oculomotor palsy, a fixed pupillary dilation and descending weakness in the absence of fever is typical of botulism. Outcome is usually favorable with a slow but full neurological recovery.

Identifiants

pubmed: 32061395
pii: S0248-8663(20)30041-2
doi: 10.1016/j.revmed.2020.01.006
pii:
doi:

Types de publication

Case Reports Journal Article Review

Langues

fre

Sous-ensembles de citation

IM

Pagination

485-488

Informations de copyright

Copyright © 2020 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.

Auteurs

M Gendrot (M)

Service de médecine interne, université Paris Descartes, AP-HP Centre-université de Paris, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris.

A Passeron (A)

Service de médecine interne, université Paris Descartes, AP-HP Centre-université de Paris, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris.

A Michon (A)

Service de médecine interne, université Paris Descartes, AP-HP Centre-université de Paris, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris.

J Pouchot (J)

Service de médecine interne, université Paris Descartes, AP-HP Centre-université de Paris, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris. Electronic address: jacques.pouchot@aphp.fr.

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Classifications MeSH