Importance of colostrum IgG antibodies level for prevention of infection with Cryptosporidium parvum in neonatal dairy calves.
Calf
Cattle
Cryptosporidiosis
Cryptosporidium
Diarrhea
Journal
Preventive veterinary medicine
ISSN: 1873-1716
Titre abrégé: Prev Vet Med
Pays: Netherlands
ID NLM: 8217463
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
28
06
2019
revised:
20
01
2020
accepted:
21
01
2020
pubmed:
18
2
2020
medline:
21
10
2020
entrez:
18
2
2020
Statut:
ppublish
Résumé
Cryptosporidiosis is one of the most common zoonosis worldwide, causing intestinal infection to both humans and livestock. The purpose of this study was to assess whether the level of anti-C. parvum IgG antibodies transferred through colostrum from dams to newborn calves impacts the susceptibility to cryptosporidiosis. A number of 50 dams and their healthy newborns were included in the study. Colostrum samples were collected within 12 h after birth and anti-C. parvum IgG antibody levels were determined by single radial immunodiffusion. The health condition of the newborns was daily monitored, and fecal samples were collected at first diarrheic episode of a calf. In all dams, the anti-C. parvum IgG antibody concentration in colostrum varied between 570 and 4070 mg/dl; in dams who gave birth to calves with diarrhea and were C. parvum-positive, the antibody concentration in colostrum varied between 680 and 3680 mg/dl (Table 1). The point-biserial correlation showed a negative correlation between the levels of anti-C. parvum antibodies and manifestation of clinical cryptosporidiosis (r=-0.425). Our findings highlight the importance of IgG levels in colostrum received by neonatal calves during their first day of life for prevention of C. parvum infection.
Identifiants
pubmed: 32066023
pii: S0167-5877(19)30425-8
doi: 10.1016/j.prevetmed.2020.104904
pmc: PMC7114226
pii:
doi:
Substances chimiques
Antibodies, Protozoan
0
Immunoglobulin G
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
104904Informations de copyright
Copyright © 2020. Published by Elsevier B.V.
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