Implementation of ezTrack open-source pipeline for quantifying rat locomotor behavior: Comparison to commercially available software.
Elevated plus maze
Locomotor activity
Open field test
Open source
Regions of interest
Journal
Neuroscience letters
ISSN: 1872-7972
Titre abrégé: Neurosci Lett
Pays: Ireland
ID NLM: 7600130
Informations de publication
Date de publication:
01 04 2020
01 04 2020
Historique:
received:
13
12
2019
revised:
31
01
2020
accepted:
13
02
2020
pubmed:
19
2
2020
medline:
20
4
2021
entrez:
19
2
2020
Statut:
ppublish
Résumé
Animal tracking software is an important tool to record and analyze locomotor activity during behavioral assays that provides considerable advantages over traditional manual scoring approaches (e.g., counting line crosses on a grid overlay or using a stopwatch to score time spent in regions of interest). Although several options are available to researchers, tracking software is often costly or requires advanced technical knowledge to operate efficiently. In this study, a free open-source behavioral tracking pipeline called ezTrack was compared to commercially available software for assessing rat locomotor behavior and time spent in regions of interest during elevated plus maze (EPM) and open field test (OFT) assays. ezTrack produced nearly identical results to the commercial software. Overall, these results suggest that ezTrack is a cost-effective approach to quantify some aspects of behavior in these tasks.
Identifiants
pubmed: 32067987
pii: S0304-3940(20)30109-9
doi: 10.1016/j.neulet.2020.134839
pii:
doi:
Types de publication
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
134839Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest No conflicts of interests are declared by the authors.