Evaluation of Dose-Fractionated Polymyxin B on Acute Kidney Injury Using a Translational
Acute Kidney Injury
/ drug therapy
Animals
Anti-Bacterial Agents
/ administration & dosage
Area Under Curve
Cell Adhesion Molecules
/ metabolism
Disease Models, Animal
Dose-Response Relationship, Drug
Kidney Function Tests
Male
Polymyxin B
/ administration & dosage
Rats
Rats, Sprague-Dawley
Translational Research, Biomedical
acute kidney injury
animal model
colistin
pharmacodynamic
pharmacokinetic
polymyxin B
polymyxins
toxicodynamic
urinary biomarker
Journal
Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061
Informations de publication
Date de publication:
21 04 2020
21 04 2020
Historique:
received:
19
11
2019
accepted:
12
02
2020
pubmed:
20
2
2020
medline:
7
4
2021
entrez:
20
2
2020
Statut:
epublish
Résumé
We investigated dose-fractionated polymyxin B (PB) on acute kidney injury (AKI). PB at 12 mg of drug/kg of body weight per day (once, twice, and thrice daily) was administered in rats over 72 h. The thrice-daily group demonstrated the highest KIM-1 increase (
Identifiants
pubmed: 32071049
pii: AAC.02300-19
doi: 10.1128/AAC.02300-19
pmc: PMC7179599
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Cell Adhesion Molecules
0
Havcr1protein, rat
0
Polymyxin B
J2VZ07J96K
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2020 American Society for Microbiology.
Références
BMJ. 1996 Feb 10;312(7027):338-45
pubmed: 8611830
Antimicrob Agents Chemother. 2017 Mar 24;61(4):
pubmed: 28167560
Nat Biotechnol. 2010 May;28(5):478-85
pubmed: 20458318
Antimicrob Agents Chemother. 2014 May;58(5):2740-6
pubmed: 24566187
Pharmacotherapy. 2015 Jan;35(1):28-33
pubmed: 25266910
Kidney Int. 2007 Oct;72(8):985-93
pubmed: 17687258
Annu Rev Pharmacol Toxicol. 2008;48:463-93
pubmed: 17937594
Infect Drug Resist. 2018 Oct 10;11:1645-1658
pubmed: 30349322
Antimicrob Agents Chemother. 2011 Sep;55(9):4044-9
pubmed: 21709095
J Basic Clin Pharm. 2016 Mar;7(2):27-31
pubmed: 27057123
Antimicrob Agents Chemother. 2018 Jul 27;62(8):
pubmed: 29844039
Antimicrob Agents Chemother. 2008 Mar;52(3):1159-61
pubmed: 18180359
J Antimicrob Chemother. 2012 Feb;67(2):452-9
pubmed: 22127588
Diagn Microbiol Infect Dis. 2015 Jun;82(2):165-71
pubmed: 25801780
J Antimicrob Chemother. 2019 Aug 1;74(8):2326-2334
pubmed: 31065686
Ther Drug Monit. 2012 Aug;34(4):467-76
pubmed: 22722776
Antibiotics (Basel). 2019 Mar 14;8(1):
pubmed: 30875778
Br J Pharmacol. 2009 Jul;157(6):907-21
pubmed: 19508398
Antimicrob Agents Chemother. 2016 Sep 23;60(10):5742-51
pubmed: 27431226
Cell Mol Life Sci. 2014 Apr;71(8):1547-8
pubmed: 24589705
Antimicrob Agents Chemother. 2017 Feb 23;61(3):
pubmed: 27993859
Diagn Microbiol Infect Dis. 2008 Feb;60(2):163-7
pubmed: 17916420
Pharmacotherapy. 2019 Jan;39(1):10-39
pubmed: 30710469
Jpn J Infect Dis. 2015;68(4):318-20
pubmed: 25720641
Crit Care Med. 2001 Apr;29(4 Suppl):N75-81
pubmed: 11292879
Antimicrob Agents Chemother. 2012 Sep;56(9):4625-9
pubmed: 22687519
Expert Opin Drug Saf. 2015;14(11):1687-701
pubmed: 26365594
Expert Rev Anti Infect Ther. 2014 May;12(5):531-3
pubmed: 24666285
Antimicrob Agents Chemother. 2013 Dec;57(12):6319-24
pubmed: 24100504
Nat Biotechnol. 2010 May;28(5):446-54
pubmed: 20458314
Ann Pharmacother. 1999 Sep;33(9):960-7
pubmed: 10492501
Antimicrob Agents Chemother. 2017 Oct 24;61(11):
pubmed: 28807910