Postoperative surveillance and long-term outcome after endovascular aortic aneurysm repair in the Netherlands: study protocol for the retrospective ODYSSEUS study.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
18 02 2020
Historique:
entrez: 21 2 2020
pubmed: 23 2 2020
medline: 17 2 2021
Statut: epublish

Résumé

Strict imaging surveillance protocols to detect complications following endovascular aneurysm repair (EVAR) are common practice. However, controversy exists as to whether all EVAR patients need intense surveillance. The 2019 European Society for Vascular Surgery guidelines for management of abdominal aortic aneurysm (AAA) suggest that patients may be considered for limited follow-up with imaging if classified as 'low risk' for complications based on their initial postoperative imaging. The current study aims to investigate the intervention-free survival and overall survival stratified for patients with and without yearly imaging surveillance. The Observing a Decade of Yearly Standardised Surveillance in EVAR patients with Ultrasound or CT Scan study comprises a national multicentre retrospective cohort study in 17 medical centres. Consecutive patients with an asymptomatic or symptomatic infrarenal AAA who underwent EVAR between January 2007 and January 2012 will be included in this study with follow-up until December 2018. Clinical variables and all follow-up information will be retrieved in extensive data collection from the patient's medical records. In addition, an e-survey was sent to vascular surgeons at the 17 participating centres to gauge their opinions regarding the possibility of safely reducing the frequency of imaging surveillance. Primary endpoints are intervention after EVAR and aneurysm-related mortality. The initial estimated sample size is 1997 patients. The study has been approved by the Medical Ethics Review Committee of the Amsterdam UMC, location Academic Medical Centre, Amsterdam, the Netherlands. Study findings will be disseminated via presentations at conferences and publications in peer-reviewed journal. The Netherlands Trial Registry, NL6953 (old: NTR28773).

Identifiants

pubmed: 32075831
pii: bmjopen-2019-033584
doi: 10.1136/bmjopen-2019-033584
pmc: PMC7045090
doi:

Banques de données

NTR
['NTR28773']

Types de publication

Journal Article Multicenter Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e033584

Investigateurs

J W Elshof (JW)
Bhp Elsman (B)
J F Hamming (JF)
J A van Herwaarden (JA)
Rhj Kropman (R)
M M Lensvelt (MM)
P P Poyck (PP)
Gwh Schurink (G)
Aaea de Smet (A)
S M van Sterkenburg (SM)
C Ünlü (C)
A C Vahl (AC)
Hjm Verhagen (H)
Pwhe Vriens (P)
Jppm de Vries (J)
J J Wever (JJ)
W Wisselink (W)
C J Zeebregts (CJ)

Informations de copyright

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Anna Catharina Maria Geraedts (ACM)

Surgery, Amsterdam University Medical Centres, Amsterdam, Noord-Holland, The Netherlands.

Sylvana de Mik (S)

Surgery, Amsterdam University Medical Centres, Amsterdam, Noord-Holland, The Netherlands.

Dirk Ubbink (D)

Surgery, Amsterdam University Medical Centres, Amsterdam, Noord-Holland, The Netherlands.

Mark Koelemay (M)

Surgery, Amsterdam University Medical Centres, Amsterdam, Noord-Holland, The Netherlands.

Ron Balm (R)

Surgery, Amsterdam University Medical Centres, Amsterdam, Noord-Holland, The Netherlands r.balm@amsterdamumc.nl.

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