Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin.

Agaricales Alkaloids / chemistry Animals Hallucinogens / chemistry Indoles / chemistry Mice Molecular Structure Organophosphates / chemistry Organophosphorus Compounds / chemistry Psilocybin / chemistry Tryptamines / chemistry

Journal

Journal of natural products
ISSN: 1520-6025
Titre abrégé: J Nat Prod
Pays: United States
ID NLM: 7906882

Informations de publication

Date de publication:
28 02 2020
Historique:
pubmed: 23 2 2020
medline: 6 3 2021
entrez: 21 2 2020
Statut: ppublish

Résumé

A general synthetic method was developed to access known tryptamine natural products present in psilocybin-producing mushrooms.

Identifiants

DOI: 10.1021/acs.jnatprod.9b01061 PMID: 32077284
pubmed: 32077284
doi: 10.1021/acs.jnatprod.9b01061
doi:

Substances chimiques

Alkaloids 0
Hallucinogens 0
Indoles 0
N, N, N-trimethyl-4-phosphoryloxytryptamine 0
Organophosphates 0
Organophosphorus Compounds 0
Tryptamines 0
baeocystin 22KW205WF2
Psilocybin 2RV7212BP0
tryptamine 422ZU9N5TV

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

461-467

Subventions

Organisme : NIDA NIH HHS
ID : R01 DA041336
Pays : United States
Organisme : NIMH NIH HHS
ID : T32 MH018399
Pays : United States

Auteurs

Alexander M Sherwood (AM)

Usona Institute , 2780 Woods Hollow Road , Madison , Wisconsin 53711 , United States.
ORCID: 0000-0003-0895-0791

Adam L Halberstadt (AL)

Department of Psychiatry , University of California San Diego , La Jolla , California 92093 , United States.
Research Service , VA San Diego Healthcare System , San Diego , California 92161 , United States.

Adam K Klein (AK)

Department of Psychiatry , University of California San Diego , La Jolla , California 92093 , United States.

John D McCorvy (JD)

Department of Cell Biology, Neurobiology, and Anatomy , Medical College of Wisconsin , Milwaukee , Wisconsin 53226 , United States.

Kristi W Kaylo (KW)

Usona Institute , 2780 Woods Hollow Road , Madison , Wisconsin 53711 , United States.

Robert B Kargbo (RB)

Usona Institute , 2780 Woods Hollow Road , Madison , Wisconsin 53711 , United States.

Poncho Meisenheimer (P)

Usona Institute , 2780 Woods Hollow Road , Madison , Wisconsin 53711 , United States.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Champignons › Basidiomycota › Agaricales › Synthesis and Biological Evaluation of...
questionsmedicales.fr › Composés hétérocycliques › Alcaloïdes › Synthesis and Biological Evaluation of...
questionsmedicales.fr › Eucaryotes › Animaux › Synthesis and Biological Evaluation of...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Psychoanaleptiques › Hallucinogènes › Synthesis and Biological Evaluation of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Indoles › Synthesis and Biological Evaluation of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Synthesis and Biological Evaluation of...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Synthesis and Biological Evaluation of...
questionsmedicales.fr › Composés chimiques organiques › Composés organiques du phosphore › Organophosphates › Synthesis and Biological Evaluation of...
questionsmedicales.fr › Composés chimiques organiques › Composés organiques du phosphore › Synthesis and Biological Evaluation of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Indolizine › Indolizidines › Alcaloïdes indoliques › Psilocybine › Synthesis and Biological Evaluation of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Indoles › Tryptamines › Synthesis and Biological Evaluation of...