Keel bone fractures induce a depressive-like state in laying hens.
Animal Husbandry
/ ethics
Animal Welfare
/ ethics
Animals
Avian Proteins
/ genetics
Chickens
Doublecortin Domain Proteins
Female
Fractures, Bone
/ complications
Gene Expression
Hippocampus
/ metabolism
Housing, Animal
/ ethics
Microtubule-Associated Proteins
/ genetics
Neurogenesis
/ physiology
Neurons
/ metabolism
Neuropeptides
/ genetics
Poultry Diseases
/ pathology
Reproduction
/ genetics
Sternum
/ injuries
Stress, Psychological
/ etiology
Trauma Severity Indices
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
20 02 2020
20 02 2020
Historique:
received:
30
09
2019
accepted:
03
02
2020
entrez:
22
2
2020
pubmed:
23
2
2020
medline:
13
11
2020
Statut:
epublish
Résumé
In commercial flocks of laying hens, keel bone fractures (KBFs) are prevalent and associated with behavioural indicators of pain. However, whether their impact is severe enough to induce a depressive-like state of chronic stress is unknown. As chronic stress downregulates adult hippocampal neurogenesis (AHN) in mammals and birds, we employ this measure as a neural biomarker of subjective welfare state. Radiographs obtained longitudinally from Lohmann Brown laying hens housed in a commercial multi-tier aviary were used to score the severity of naturally-occurring KBFs between the ages of 21-62 weeks. Individual birds' transitions between aviary zones were also recorded. Focal hens with severe KBFs at 3-4 weeks prior to sampling (n = 15) had lower densities of immature doublecortin-positive (DCX
Identifiants
pubmed: 32080271
doi: 10.1038/s41598-020-59940-1
pii: 10.1038/s41598-020-59940-1
pmc: PMC7033198
doi:
Substances chimiques
Avian Proteins
0
Doublecortin Domain Proteins
0
Microtubule-Associated Proteins
0
Neuropeptides
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3007Références
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