Sickle Cell Disease is Associated with Increased Morbidity, Resource Utilization, and Readmissions after Common Abdominal Surgeries: A Multistate Analysis, 2007-2014.
Adult
Anemia, Sickle Cell
/ diagnosis
Appendectomy
/ adverse effects
Blood Transfusion
/ statistics & numerical data
Cholecystectomy
/ adverse effects
Female
Hospital Costs
/ statistics & numerical data
Humans
Hysterectomy
/ adverse effects
Length of Stay
/ statistics & numerical data
Male
Outcome Assessment, Health Care
Patient Readmission
/ statistics & numerical data
Postoperative Complications
/ blood
Reoperation
/ statistics & numerical data
Risk Adjustment
/ methods
Risk Factors
United States
/ epidemiology
Abdominal surgery
Administrative database research
Healthcare disparities
Outcomes research
Sickle cell anemia
Sickle cell disease
Journal
Journal of the National Medical Association
ISSN: 1943-4693
Titre abrégé: J Natl Med Assoc
Pays: United States
ID NLM: 7503090
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
21
02
2019
revised:
15
01
2020
accepted:
23
01
2020
pubmed:
25
2
2020
medline:
27
2
2021
entrez:
25
2
2020
Statut:
ppublish
Résumé
Sickle cell disease (SCD), the most commonly inherited hemoglobinopathy in the United States, increases the likelihood of postoperative complications, resulting in higher costs and readmissions. We used a retrospective cohort study to explore SCD's influence on postoperative complications and readmissions after cholecystectomy, appendectomy, and hysterectomy. We used an administrative database's 2007-2014 data from California, Florida, New York, Maryland, and Kentucky. 1,934,562 patients aged ≥18 years were included. Compared to non-SCD patients, SCD patients experienced worse outcomes: increased odds of blood transfusion and major and minor complications, higher adjusted odds of 30- and 90-day readmissions, longer length of stay, and higher total hospital charges. Sickle cell disease patients are at high risk for poor outcomes based on their demographic characteristics. Therefore, perioperative physicians including hematologists, anesthesiologists, and surgeons need to take this knowledge into consideration for management and counselling of SCD patients on the risks of surgery and recovery.
Identifiants
pubmed: 32089275
pii: S0027-9684(19)30059-8
doi: 10.1016/j.jnma.2020.01.001
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
198-208Informations de copyright
Copyright © 2020 National Medical Association. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of Interest None.