Readmission to hospital following laparoscopic cholecystectomy: a meta-analysis.


Journal

Anaesthesiology intensive therapy
ISSN: 1731-2531
Titre abrégé: Anaesthesiol Intensive Ther
Pays: Poland
ID NLM: 101472620

Informations de publication

Date de publication:
2020
Historique:
pubmed: 25 2 2020
medline: 9 2 2021
entrez: 25 2 2020
Statut: ppublish

Résumé

Laparoscopic cholecystectomy (LC) is one of the most commonly performed surgical procedures. Despite this, patterns of readmission following LC are not well defined. This meta-analysis aimed to determine rates and predictors of readmission. An ethically approved International Prospective Register of Systematic Reviews (PROSPERO)-registered meta-analysis was undertaken searching PubMed, Scopus, Web of Science and Cochrane Library databases from January 2013-June 2018 adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Published literature potentially suitable for data analysis was graded using methodological index for non-randomised studies (MINORS) criteria; papers scoring ≥ 16/24 for comparative and ≥ 10/16 for non-comparative studies were included. A meta-analysis of potential risk factors was performed by computing the odds ratio using Mantel-Haenszel method and fixed-effects model with 95% confidence intervals. Three thousand and eight hundred thirty-two articles were reduced to 44 studies qualifying for a final analysis of 1,573,715 laparoscopic cholecystectomies from 25 countries. Overall readmission rate was 3.3% (range: 0.0-11.7%); 52,628 readmissions out of 1,573,715 LCs. Surgical complications accounted for 76% of reported reasons for readmission, predominantly bile duct complications (33%), wound infection (17%) and nausea and vomiting (9%). Pain (15%) and cardiorespiratory complications (8%) account for the remainder. Obesity, single port LC and day case LC were not associated with increased rates. Pain, nausea and vomiting and surgical complications, particularly bile duct obstruction are the most common causes for readmission. Intra-operative cholangiography may reduce readmission rates. Causes for readmission were inconsistently reported throughout. The mean readmission rate of 3.3% may act as a quality benchmark for improving LC, and clearer reporting of reasons for readmission are required to advance care.

Sections du résumé

BACKGROUND
Laparoscopic cholecystectomy (LC) is one of the most commonly performed surgical procedures. Despite this, patterns of readmission following LC are not well defined. This meta-analysis aimed to determine rates and predictors of readmission.
METHODS
An ethically approved International Prospective Register of Systematic Reviews (PROSPERO)-registered meta-analysis was undertaken searching PubMed, Scopus, Web of Science and Cochrane Library databases from January 2013-June 2018 adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Published literature potentially suitable for data analysis was graded using methodological index for non-randomised studies (MINORS) criteria; papers scoring ≥ 16/24 for comparative and ≥ 10/16 for non-comparative studies were included. A meta-analysis of potential risk factors was performed by computing the odds ratio using Mantel-Haenszel method and fixed-effects model with 95% confidence intervals.
RESULTS
Three thousand and eight hundred thirty-two articles were reduced to 44 studies qualifying for a final analysis of 1,573,715 laparoscopic cholecystectomies from 25 countries. Overall readmission rate was 3.3% (range: 0.0-11.7%); 52,628 readmissions out of 1,573,715 LCs. Surgical complications accounted for 76% of reported reasons for readmission, predominantly bile duct complications (33%), wound infection (17%) and nausea and vomiting (9%). Pain (15%) and cardiorespiratory complications (8%) account for the remainder. Obesity, single port LC and day case LC were not associated with increased rates.
CONCLUSIONS
Pain, nausea and vomiting and surgical complications, particularly bile duct obstruction are the most common causes for readmission. Intra-operative cholangiography may reduce readmission rates. Causes for readmission were inconsistently reported throughout. The mean readmission rate of 3.3% may act as a quality benchmark for improving LC, and clearer reporting of reasons for readmission are required to advance care.

Identifiants

pubmed: 32090306
pii: 39867
doi: 10.5114/ait.2020.92967
pmc: PMC10173143
pii:
doi:

Types de publication

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

47-55

Commentaires et corrections

Type : CommentIn

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Auteurs

Caroline McIntyre (C)

Department of Surgery, Letterkenny University Hospital, Donegal, Ireland.

Alison Johnston (A)

Emergency Surgery Outcome Advancement Project, Donegal Clinical and Research Academy, Donegal, Ireland.

Deirdre Foley (D)

Department of Surgery, Letterkenny University Hospital, Donegal, Ireland.

Jack Lawler (J)

Department of Surgery, Letterkenny University Hospital, Donegal, Ireland.

Magda Bucholc (M)

EU INTERREG Centre for Personalised Medicine project, Intelligent Systems Research Centre, School of Computing, Engineering and Intelligent Systems, Ulster University, Northern Ireland.

Louise Flanagan (L)

Emergency Surgery Outcome Advancement Project, Donegal Clinical and Research Academy, Donegal, Ireland.

Michael Sugrue (M)

Department of Surgery, Letterkenny University Hospital, Donegal, Ireland.
Emergency Surgery Outcome Advancement Project, Donegal Clinical and Research Academy, Donegal, Ireland.
EU INTERREG Centre for Personalised Medicine project, Intelligent Systems Research Centre, School of Computing, Engineering and Intelligent Systems, Ulster University, Northern Ireland.

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