Adherence to Gluten-free Diet in a Celiac Pediatric Population Referred to the General Pediatrician After Remission.
Journal
Journal of pediatric gastroenterology and nutrition
ISSN: 1536-4801
Titre abrégé: J Pediatr Gastroenterol Nutr
Pays: United States
ID NLM: 8211545
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
pubmed:
26
2
2020
medline:
22
6
2021
entrez:
26
2
2020
Statut:
ppublish
Résumé
Assessment of adherence to gluten-free diet in celiac disease (CD) is generally recommended. Few data are available about consequences of transition from the referral center to the general pediatrician (GP) once remission is achieved. Adherence was assessed in patients referred to the GP for an annual basis follow-up, called back for re-evaluation. Immunoglobulin A (IgA) antitissue transglutaminase (anti-tTG) antibodies and the Biagi score (BS) were determined at last follow-up at the referral center (V1), and at re-evaluation (V2). Patients were classified as adherent (BS 3-4, IgA anti-tTG <7 U/mL) and nonadherent (BS 0-2, IgA anti-tTG ≥7). Scores of adherence were correlated with personal and clinical data. We evaluated 200 patients. Overall, we found good adherence rates in 94.95% of patients at V1 and 83.5% at V2. IgA anti-tTG were negative in 100% at V1 and 96.97% at V2. BS is 3 to 4 in 94.5% at V1 and 84% at V2. Adherence at V2 was significantly worse than V1 (P < 0.001). No significant associations were found between scores of adherence and sex, symptoms and age at diagnosis, family history of CD, comorbidity, and diagnosis by endoscopy. Age 13 years or older represents a risk factor for lack of compliance at V1 (P = 0.02) and V2 (P = 0.04), and foreign nationality at V2 (P = 0.001). The BS, serology, and a clinical interview, integrated, are reliable tools for assessing pediatric adherence to gluten-free diet. We argue that referring patients to the GP after remission of CD is important, but the process must be improved and recommendations are required.
Identifiants
pubmed: 32097372
doi: 10.1097/MPG.0000000000002676
pii: 00005176-202007000-00022
doi:
Substances chimiques
Autoantibodies
0
Immunoglobulin A
0
Transglutaminases
EC 2.3.2.13
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
78-82Références
Husby S, Koletzko S, Korponay-Szabò IR, et al. European society for pediatric gastroenterology, hepatology, and nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr 2012; 54:136–160.
Hoffenberg EJ, MacKenzie T, Barriga KJ, et al. A prospective study of the incidence of childhood celiac disease. J Pediatr 2003; 143:308–314.
McGowan KE, Castiglione DA, Butzner JD. The changing face of childhood celiac disease in North America: impact of serological testing. Pediatrics 2009; 124:1572–1578.
Myléus A, Reilly NR, Green PHR. Rate, risk factors, and outcomes of nonadherence in pediatric patients with celiac disease: a systematic review. Clin Gastroenterol Hepatol 2020; 18:562–573.
Hopman EGD, Le Cessie S, Von Blomberg BME, et al. Nutritional management of the gluten-free diet in young people with celiac disease in The Netherlands. J Pediatr Gastroenterol Nutr 2006; 43:102–108.
Errichiello S, Esposito O, Di Mase R, et al. Celiac disease: Predictors of compliance with a gluten-free diet in adolescents and young adults. J Pediatr Gastroenterol Nutr 2010; 50:54–60.
Jadrešin O, Mišak Z, Sanja K, et al. Compliance with gluten-free diet in children with coeliac disease. J Pediatr Gastroenterol Nutr 2008; 47:344–348.
Czaja-Bulsa G, Bulsa M. Adherence to gluten-free diet in children with celiac disease. Nutrients 2018; 10:pii: E1424.
Chauhan JC, Kumar P, Dutta AK, et al. Assessment of dietary compliance to gluten free diet and psychosocial problems in Indian children with celiac disease. Indian J Pediatr 2010; 77:649–654.
Charalampopoulos D, Panayiotou J, Chouliaras G, et al. Determinants of adherence to gluten-free diet in Greek children with coeliac disease: a cross-sectional study. Eur J Clin Nutr 2013; 67:615–619.
Mehta P, Pan Z, Riley MD, et al. Adherence to a gluten-free diet: assessment by dietician interview and serology. J Pediatr Gastroenterol Nutr 2018; 66:e67–e70.
Pietzak MM. Follow-up of patients with celiac disease: achieving compliance with treatment. Gastroenterology 2005; 128:S135–S141.
Zanchi C, Ventura A, Martelossi S, et al. Rapid anti-transglutaminase assay and patient interview for monitoring dietary compliance in celiac disease. Scand J Gastroenterol 2013; 48:764–766.
Monzani A, Oderda G, Rapa A. Use of deamidated gliadin peptide antibodies to monitor diet compliance in childhood celiac disease. J Pediatr Gastroenterol Nutr 2011; 53:55–60.
Rubio-Tapia A, Hill ID, Kelly CP, et al. ACG clinical guidelines: diagnosis and management of celiac disease. Am J Gastroenterol 2013; 108:656–676.
Simpson S, Thompson T. Nutrition assessment in celiac disease. Gastrointest Endosc Clin N Am 2012; 22:797–809.
See J, Murray JA. Gluten-free diet: the medical and nutrition management of celiac disease. Nutr Clin Pract 2006; 21:1–15.
Rodrigo L, Pérez-Martinez I, Lauret-Braña E, et al. Descriptive study of the different tools used to evaluate the adherence to a gluten-free diet in celiac disease patients. Nutrients 2018; 10:pii: E1777.
Johansson K, Norström F, Nordyke K, et al. Celiac dietary adherence test simplifies determining adherence to a gluten-free diet in Swedish adolescents. J Pediatr Gastroenterol Nutr 2019; 69:575–580.
Biagi F, Bianchi PI, Marchese A, et al. A score that verifies adherence to a gluten-free diet: a cross-sectional, multicentre validation in real clinical life. Br J Nutr 2012; 108:1884–1888.
Biagi F, Andrealli A, Bianchi PI, et al. A gluten-free diet score to evaluate dietary compliance in patients with coeliac disease. Br J Nutr 2009; 102:882–887.
Hill ID, Dirks MH, Liptak GS, et al. Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 2005; 40:1–19.
Wessels MMS, Te Lintelo M, Vriezinga SL, et al. Assessment of dietary compliance in celiac children using a standardized dietary interview. Clin Nutr 2018; 37:1000–1004.
Syage JA, Kelly CP, Dickason MA, et al. Determination of gluten consumption in celiac disease patients on a gluten-free diet. Am J Clin Nutr 2018; 107:201–207.
Rajani S, Sawyer-Bennett J, Shirton L, et al. Patient and parent satisfaction with a dietitian- and nurse-led celiac disease clinic for children at the Stollery Children's Hospital, Edmonton, Alberta. Can J Gastroenterol 2013; 278:463–466.
Barnea L, Mozer-Glassberg Y, Hojsak I, et al. Pediatric celiac disease patients who are lost to follow-up have a poorly controlled disease. Digestion 2014; 90:248–253.
Ludvigsson JF, Agreus L, Ciacci C, et al. Transition from childhood to adulthood in coeliac disease: the Prague consensus report. Gut 2016; 65:1242–1251.