Contemporary conditional cancer-specific survival after radical nephroureterectomy in patients with nonmetastatic urothelial carcinoma of upper urinary tract.
SEER database
disease stage
epidemiology
survival benefit
tumor characteristics
Journal
Journal of surgical oncology
ISSN: 1096-9098
Titre abrégé: J Surg Oncol
Pays: United States
ID NLM: 0222643
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
24
01
2020
accepted:
13
02
2020
pubmed:
29
2
2020
medline:
29
5
2020
entrez:
29
2
2020
Statut:
ppublish
Résumé
To examine the effect of conditional survival on 5-year cancer-specific survival (CSS) probability after radical nephroureterectomy (RNU) in a contemporary cohort of patients with non-metastatic urothelial carcinoma of the upper urinary tract (UTUC). Within the Surveillance, Epidemiology and End Results database (2004-2015), 6826 patients were identified. Conditional 5-year CSS estimates were assessed after event-free follow-up duration. Multivariable Cox regression (MCR) models predicted cancer-specific mortality (CSM) according to event-free follow-up length. Overall, 956 (14.0%) were T A direct relationship exists between event-free follow-up and survival probability after RNU. From a clinical perspective, such survival estimates may have particular importance during preoperative counseling.
Sections du résumé
BACKGROUND AND OBJECTIVES
OBJECTIVE
To examine the effect of conditional survival on 5-year cancer-specific survival (CSS) probability after radical nephroureterectomy (RNU) in a contemporary cohort of patients with non-metastatic urothelial carcinoma of the upper urinary tract (UTUC).
METHODS
METHODS
Within the Surveillance, Epidemiology and End Results database (2004-2015), 6826 patients were identified. Conditional 5-year CSS estimates were assessed after event-free follow-up duration. Multivariable Cox regression (MCR) models predicted cancer-specific mortality (CSM) according to event-free follow-up length.
RESULTS
RESULTS
Overall, 956 (14.0%) were T
CONCLUSIONS
CONCLUSIONS
A direct relationship exists between event-free follow-up and survival probability after RNU. From a clinical perspective, such survival estimates may have particular importance during preoperative counseling.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1154-1161Informations de copyright
© 2020 Wiley Periodicals, Inc.
Références
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