Regenerative Peripheral Nerve Interfaces for Prevention and Management of Neuromas.

Amputation Neuroma pain Pain Peripheral nerve Phantom limb pain RPNI Regenerative peripheral nerve interface

Journal

Clinics in plastic surgery
ISSN: 1558-0504
Titre abrégé: Clin Plast Surg
Pays: United States
ID NLM: 0424767

Informations de publication

Date de publication:
Apr 2020
Historique:
entrez: 3 3 2020
pubmed: 3 3 2020
medline: 8 9 2020
Statut: ppublish

Résumé

Symptomatic neuromas are a common cause of postamputation pain that can lead to significant disability. Regenerative peripheral nerve interface surgery is performed to treat symptomatic neuromas and prevent the development of neuromas. This review delineates the clinical problem of postamputation pain, describes the limitations of the available treatment methods, and highlights the need for an effective treatment strategy that leverages the biologic processes of nerve regeneration and muscle reinnervation. The evidence supporting use of regenerative peripheral nerve interface surgery to mitigate neuroma formation is discussed and the rationale behind the efficacy of regenerative peripheral nerve interfaces is explored.

Identifiants

pubmed: 32115057
pii: S0094-1298(20)30004-3
doi: 10.1016/j.cps.2020.01.004
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

311-321

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors have nothing to disclose.

Auteurs

Katherine B Santosa (KB)

Section of Plastic Surgery, Department of Surgery, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

Jeremie D Oliver (JD)

Mayo Clinic School of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA.

Paul S Cederna (PS)

Section of Plastic Surgery, Department of Surgery, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

Theodore A Kung (TA)

Section of Plastic Surgery, Department of Surgery, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address: thekung@med.umich.edu.

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Classifications MeSH