The Interface between Keratin Structurotype and Human Disease.

Cytoskeleton Humans Intermediate Filaments Keratins

Journal

Structure (London, England : 1993)
ISSN: 1878-4186
Titre abrégé: Structure
Pays: United States
ID NLM: 101087697

Informations de publication

Date de publication:
03 03 2020
Historique:
entrez: 5 3 2020
pubmed: 5 3 2020
medline: 9 7 2020
Statut: ppublish

Résumé

In this issue of Structure, Coulombe and coworkers (Lee et al., 2020) present the crystal structure of the keratin 5/14 2B heterodimeric complex containing the keratin 14 substitution C367A. The authors identify a 2B-2B contact interface important to the elongation of mature keratin 5/14 filaments.

Identifiants

DOI: 10.1016/j.str.2020.02.002 PMID: 32130887 PMC: PMC7252399
pubmed: 32130887
pii: S0969-2126(20)30043-5
doi: 10.1016/j.str.2020.02.002
pmc: PMC7252399
mid: NIHMS1591343
pii:
doi:

Substances chimiques

Keratins 68238-35-7

Types de publication

Journal Article Research Support, N.I.H., Extramural Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

271-273

Subventions

Organisme : NIAMS NIH HHS
ID : K08 AR070290
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Références

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pubmed: 1606966
Cell. 1991 Sep 20;66(6):1301-11
pubmed: 1717157
J Mol Biol. 1993 Mar 20;230(2):436-52
pubmed: 7681879
Bioessays. 2016 Mar;38(3):232-43
pubmed: 26763143
Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16206-11
pubmed: 17050693
J Cell Biol. 2015 Apr 13;209(1):59-72
pubmed: 25869667
Yale J Biol Med. 2020 Mar 27;93(1):3-17
pubmed: 32226330
Structure. 2020 Mar 3;28(3):355-362.e4
pubmed: 31995743
EMBO J. 2019 Jun 3;38(11):
pubmed: 31036554
Nat Struct Mol Biol. 2012 Jun 17;19(7):707-15
pubmed: 22705788

Auteurs

Sherif A Eldirany (SA)

Department of Dermatology, Yale University, New Haven, CT 06520, USA.

Minh Ho (M)

Department of Dermatology, Yale University, New Haven, CT 06520, USA.

Christopher G Bunick (CG)

Department of Dermatology, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. Electronic address: christopher.bunick@yale.edu.

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Classifications MeSH

questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Cytosquelette › The Interface between Keratin Structurotype...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Interface between Keratin Structurotype...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Cytosquelette › Filaments intermédiaires › The Interface between Keratin Structurotype...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Kératines › The Interface between Keratin Structurotype...