Increased blood pressure variability during the subacute phase in patients with ischemic stroke presenting with a low ankle-brachial index.
Aged
Aged, 80 and over
Ankle Brachial Index
Blood Pressure
/ physiology
Blood Pressure Determination
Blood Pressure Monitoring, Ambulatory
Brain Ischemia
/ complications
Female
Hospitalization
Humans
Hypertension
/ diagnosis
Japan
Male
Middle Aged
Peripheral Arterial Disease
/ diagnosis
Retrospective Studies
Risk Factors
Stroke
/ complications
ambulatory blood pressure monitoring
ankle-brachial index
hypertension
stroke
Journal
Geriatrics & gerontology international
ISSN: 1447-0594
Titre abrégé: Geriatr Gerontol Int
Pays: Japan
ID NLM: 101135738
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
10
11
2019
revised:
06
02
2020
accepted:
12
02
2020
pubmed:
7
3
2020
medline:
26
8
2020
entrez:
6
3
2020
Statut:
ppublish
Résumé
This study aimed to evaluate the associations of blood pressure (BP) variability in patients with ischemic stroke during the subacute phase using ambulatory blood pressure monitoring and the ankle-brachial index (ABI). We retrospectively examined 831 consecutive patients (women 44.8%, mean age 76 ± 12 years) with acute ischemic stroke who underwent 24-h ambulatory blood pressure monitoring during the subacute phase of stroke (median 9 days from onset) and an ABI examination. BP variability was evaluated by assessing the standard deviation and coefficient of variation of systolic BP and diastolic BP. A low ABI was defined as an ABI <0.9. Of the 831 patients, 201 (24.2%) had a low ABI. Older age, lower body mass index, diabetes mellitus, chronic kidney disease, atrial fibrillation and a higher National Institutes of Health Stroke Scale score at admission were independently associated with a low ABI. The patients with a low ABI had a higher mean 24-h diastolic BP, higher standard deviation of both BP measurements (systolic BP and diastolic BP) and a higher coefficient of variation in both BP measurements than those with a higher ABI. According to the multivariable linear regression analysis, a low ABI was independently associated with increased BP variability (a high standard deviation or coefficient of variation of both BP measurements) after adjusting for baseline confounders. A low ABI was associated with increased BP variability during the subacute ischemic phase. Geriatr Gerontol Int 2020; 20: 448-454.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
448-454Subventions
Organisme : Japan Society for the Promotion of Science
ID : 18K10746
Organisme : Japan Society for the Promotion of Science
ID : 17K17907
Organisme : Japan Society for the Promotion of Science
ID : 17K17350
Informations de copyright
© 2020 Japan Geriatrics Society.
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