Bioconjugated gold nanoparticles as an efficient colorimetric sensor for cancer diagnostics.

Colorimetry Gold Limit of Detection Metal Nanoparticles Neoplasms / diagnosis Photochemotherapy / methods Photosensitizing Agents
Biosensor Cancer detection Color change Colorimetric sensor Functionalization Gold nanoparticles

Journal

Photodiagnosis and photodynamic therapy
ISSN: 1873-1597
Titre abrégé: Photodiagnosis Photodyn Ther
Pays: Netherlands
ID NLM: 101226123

Informations de publication

Date de publication:
Jun 2020
Historique:
received: 21 01 2020
revised: 15 02 2020
accepted: 28 02 2020
pubmed: 7 3 2020
medline: 15 5 2021
entrez: 6 3 2020
Statut: ppublish

Résumé

The chances of curing and reducing the adverse effect of cancer partly lie in early detection. Colorimetric sensor-based technique show promising results since the target is detected with high sensitivity but without the use of advanced/costly techniques through a simple visual color change. In most cases, gold nanoparticles (Au Nps) functionalized with biomolecules complementary to target analyte are used for colorimetric detection. The interaction of functionalized Au Nps with target analytes induce aggregation or dispersion where the color of the solution changes from red to blue or blue to red respectively, which can be visualized by the naked eyes. Such a facile technique has a high commercial viability and therefore, understanding its concept is essential. Here, some of the reported studies are discussed technically for better understanding about the invitro colorimetric detection of cancer.

Identifiants

DOI: 10.1016/j.pdpdt.2020.101699 PMID: 32135315
pubmed: 32135315
pii: S1572-1000(20)30052-1
doi: 10.1016/j.pdpdt.2020.101699
pii:
doi:

Substances chimiques

Photosensitizing Agents 0
Gold 7440-57-5

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

101699

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

K Akshaya (K)

Medical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Kelambakkam, 603103, Tamilnadu, India.

C Arthi (C)

Medical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Kelambakkam, 603103, Tamilnadu, India.

A J Pavithra (AJ)

Medical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Kelambakkam, 603103, Tamilnadu, India.

P Poovizhi (P)

Medical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Kelambakkam, 603103, Tamilnadu, India.

S Shilpa Antinate (SS)

Medical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Kelambakkam, 603103, Tamilnadu, India.

G S Hikku (GS)

Medical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Kelambakkam, 603103, Tamilnadu, India. Electronic address: gshikku@gmail.com.

K Jeyasubramanian (K)

Department of Chemistry, Mepco Schlenk Engineering College, Sivakasi 626005, Tamilnadu, India.

R Murugesan (R)

Chettinad Academy of Research and Education, Kelambakkam 603103, Tamilnadu, India.

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Titrimétrie › Colorimétrie › Bioconjugated gold nanoparticles as an...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Or › Bioconjugated gold nanoparticles as an...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Sensibilité et spécificité › Limite de détection › Bioconjugated gold nanoparticles as an...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Nanoparticules métalliques › Bioconjugated gold nanoparticles as an...
questionsmedicales.fr › Tumeurs › Bioconjugated gold nanoparticles as an...
questionsmedicales.fr › Thérapeutique › Photothérapie › Photothérapie dynamique › Bioconjugated gold nanoparticles as an...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Radiosensibilisants › Photosensibilisants › Bioconjugated gold nanoparticles as an...