Allergic and photoallergic contact dermatitis to chlorpromazine.


Journal

The Australasian journal of dermatology
ISSN: 1440-0960
Titre abrégé: Australas J Dermatol
Pays: Australia
ID NLM: 0135232

Informations de publication

Date de publication:
Aug 2020
Historique:
received: 09 12 2019
accepted: 12 01 2020
pubmed: 7 3 2020
medline: 6 7 2021
entrez: 7 3 2020
Statut: ppublish

Résumé

Chlorpromazine is known to produce both systemic phototoxic and photoallergic reactions. However, it may also cause photoallergic contact dermatitis and, albeit exceptionally, allergic contact dermatitis (ACD). We present a series of photoallergic contact dermatitis and ACD to chlorpromazine diagnosed at a tertiary centre cutaneous allergy unit between 1980 and 2019.

Identifiants

pubmed: 32141075
doi: 10.1111/ajd.13254
doi:

Substances chimiques

Antipsychotic Agents 0
Chlorpromazine U42B7VYA4P

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e351-e353

Informations de copyright

© 2020 The Australasian College of Dermatologists.

Références

Epstein S. Chlorpromazine photosensitivity. Phototoxic and photoallergic reactions. Arch. Dermatol 1968; 98: 354-63.
Katsarou A, Makris M, Zarafonitis G et al. Photoallergic contact dermatitis: the 15-year experience of a tertiary reference center in a sunny Mediterranean city. Int. J. Immunopathol. Pharmacol. 2008; 21: 725-7.
Gonçalo M, Ferguson J, Bonevalle A et al. Photopatch testing: recommendations for a European photopatch test baseline series. Contact Dermatitis 2013; 68: 239-43.
Cardoso JC, Canelas MM, Gonçalo M et al. Photopatch testing with an extended series of photoallergens: a 5-year study. Contact Dermatitis 2009; 60: 325-9.
Giomi B, Difonzo EM, Lotti L et al. Allergic and photoallergic conditions from unusual chlorpromazine exposure: report of three cases. Int. J. Dermatol. 2011; 50: 1276-8.
Monteagudo-Paz A, Salvador JS, Martinez NL et al. Pulpitis as clinical presentation of photoallergic contact dermatitis due to chlorpromazine. Allergy 2011; 66: 1503-4.
Esteve-Martínez A, Ninet Zaragoza V, de la Cuadra Oyanguren J et al. Queilitis fotoalérgica de contacto por clorpromazina: descripción de 2 casos. Actas Dermosifiliogr 2015; 106: 518-20.
Chignell CF, Motten AG, Buettner GR. Photoinduced free radicals from chlorpromazine and related phenothiazines: relationship to phenothiazine-induced photosensitization. Environ. Health Perspect 1985; 64: 103-110.

Auteurs

Alvaro Martínez-Doménech (A)

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

Marta García-Legaz Martínez (M)

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

Blanca Ferrer-Guillén (B)

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

Jorge Magdaleno-Tapial (J)

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

Cristian Valenzuela-Oñate (C)

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

Altea Esteve-Martínez (A)

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

Violeta Zaragoza-Ninet (V)

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

Amparo Pérez-Ferriols (A)

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

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Classifications MeSH