Caustic Ingestion in Children: 1 Year Experience in 3 Italian Referral Centers.


Journal

Journal of pediatric gastroenterology and nutrition
ISSN: 1536-4801
Titre abrégé: J Pediatr Gastroenterol Nutr
Pays: United States
ID NLM: 8211545

Informations de publication

Date de publication:
07 2020
Historique:
pubmed: 7 3 2020
medline: 22 6 2021
entrez: 7 3 2020
Statut: ppublish

Résumé

Despite the efforts to reduce the exposure to corrosive household products, caustic ingestion in children is currently a significant medical problem. The aims of the present study were to evaluate the clinical consequences of caustic ingestion and to identify prognostic factors that could concur in driving both diagnostic and therapeutic management. All consecutive children referred for ingestion of a caustic substance from June 2017 to June 2018 were enrolled. Medical records, laboratory and endoscopic findings were reviewed and analyzed. We enrolled 44 children with caustic ingestion. Alkaline agents were ingested by 26 of 44 (59.1%) patients, whereas acid agents were ingested by 18 of 44 patients (40.9%). Alkaline rather than acid agents were associated with a worse endoscopic score (r: 0.45) and a higher probability of early esophageal stricture occurrence (r: 0.38). The specific risk of the presence of severe esophageal lesions rose progressively with increasing number of symptoms whereas no esophageal injury was found in asymptomatic patients. Our data suggest that endoscopic evaluation is mandatory in symptomatic patients to direct therapeutic management, but it could be avoided in asymptomatic patients after accidental ingestion, particularly if the ingestion is only suspected and patients have no oropharyngeal burns.

Identifiants

pubmed: 32142003
doi: 10.1097/MPG.0000000000002685
pii: 00005176-202007000-00008
doi:

Substances chimiques

Caustics 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

19-22

Références

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Auteurs

Giovanni Di Nardo (G)

NESMOS Department, School of Medicine and Psychology, Sapienza University of Rome, Sant'Andrea University Hospital, Rome.

Pietro Betalli (P)

Pediatric Surgery Unit, Ospedale Papa Giovanni XXIII, Bergamo.

Maria Teresa Illiceto (MT)

Pediatric Gastroenterology and Endoscopic Unit "Santo Spirito" Hospital, Pescara.

Giannotti Giulia (G)

Pediatric Surgery Unit, Ospedale Papa Giovanni XXIII, Bergamo.

Luigi Martemucci (L)

Pediatric Gastroenterology Unit, A.O.R.N. Santobono-Pausilipon, Naples.

Flora Caruso (F)

Pediatric Gastroenterology Unit, A.O.R.N. Santobono-Pausilipon, Naples.

Gabriele Lisi (G)

Department of Pediatric Surgery, University of Chieti-Pescara "Gabriele D'Annunzio" - Santo Spirito Hospital, Pescara.

Giusy Romano (G)

Department of Medical and Surgical Sciences, Pediatric Unit, University "Magna Graecia" of Catanzaro, Catanzaro.

Maria Pia Villa (MP)

NESMOS Department, School of Medicine and Psychology, Sapienza University of Rome, Sant'Andrea University Hospital, Rome.

Chiara Ziparo (C)

NESMOS Department, School of Medicine and Psychology, Sapienza University of Rome, Sant'Andrea University Hospital, Rome.

Licia Pensabene (L)

Department of Medical and Surgical Sciences, Pediatric Unit, University "Magna Graecia" of Catanzaro, Catanzaro.

Francesca Vassallo (F)

NESMOS Department, School of Medicine and Psychology, Sapienza University of Rome, Sant'Andrea University Hospital, Rome.

Paolo Quitadamo (P)

Department of Pediatrics, A.O.R.N. Santobono-Pausilipon, Naples, Italy.

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