Overcoming bottlenecks in plant gene editing.


Journal

Current opinion in plant biology
ISSN: 1879-0356
Titre abrégé: Curr Opin Plant Biol
Pays: England
ID NLM: 100883395

Informations de publication

Date de publication:
04 2020
Historique:
received: 12 11 2019
revised: 30 12 2019
accepted: 22 01 2020
pubmed: 7 3 2020
medline: 18 7 2020
entrez: 7 3 2020
Statut: ppublish

Résumé

Agriculture has reached a technological inflection point. The development of novel gene editing tools and methods for their delivery to plant cells promises to increase genome malleability and transform plant biology. Whereas gene editing is capable of making a myriad of DNA sequence modifications, its widespread adoption has been hindered by a number of factors, particularly inefficiencies in creating precise DNA sequence modifications and ineffective methods for delivering gene editing reagents to plant cells. Here, we briefly overview the principles of plant genome editing and highlight a subset of the most recent advances that promise to overcome current limitations.

Identifiants

pubmed: 32143167
pii: S1369-5266(20)30003-0
doi: 10.1016/j.pbi.2020.01.002
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

79-84

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Paul Ap Atkins (PA)

Center for Genome Engineering, Center for Precision Plant Genomics and Department of Genetics, Cell Biology and Development, University of Minnesota, St. Paul, MN 55108, USA.

Daniel F Voytas (DF)

Center for Genome Engineering, Center for Precision Plant Genomics and Department of Genetics, Cell Biology and Development, University of Minnesota, St. Paul, MN 55108, USA. Electronic address: voytas@umn.edu.

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Classifications MeSH