Novel HPAIV H5N8 Reassortant (Clade 2.3.4.4b) Detected in Germany.
H5N8
HPAIV
MinION
avian influenza viruses
reassortment
third-generation sequencing
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
04 03 2020
04 03 2020
Historique:
received:
26
01
2020
revised:
21
02
2020
accepted:
02
03
2020
entrez:
8
3
2020
pubmed:
8
3
2020
medline:
20
2
2021
Statut:
epublish
Résumé
A novel H5N8 highly pathogenic avian influenza virus (HPAIV) was detected in a greater white-fronted goose in January 2020 in Brandenburg, Germany, and, in February 2020, in domestic chickens belonging to a smallholding in Baden-Wuerttemberg, Germany. Full-genome sequencing was conducted on the MinION platform, enabling further phylogenetic analyses. The virus of clade 2.3.4.4b holds six segments from a Eurasian/Asian/African HPAIV H5N8 reassortant and two segments from low pathogenic avian influenza H3N8 subtype viruses recently detected in wild birds in Central Russia. These new entries continue to show the reassortment potential of the clade 2.3.4.4 H5Nx viruses, underlining the necessity for full-genome sequencing and continuous surveillance.
Identifiants
pubmed: 32143363
pii: v12030281
doi: 10.3390/v12030281
pmc: PMC7150876
pii:
doi:
Substances chimiques
RNA, Viral
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
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