Burkitt and Burkitt-Like Lymphomas: a Systematic Review.
Antigens, CD20
/ metabolism
Antineoplastic Combined Chemotherapy Protocols
/ therapeutic use
Burkitt Lymphoma
/ genetics
Chromosomes, Human, Pair 14
/ genetics
Chromosomes, Human, Pair 8
/ genetics
Hematopoietic Stem Cell Transplantation
/ methods
Humans
Proto-Oncogene Proteins c-bcl-6
/ metabolism
Rituximab
/ administration & dosage
Translocation, Genetic
Burkitt’s lymphoma
C-MYC
CODOX-M/IVAC
DA-EPOCH-R
Endemic form
GMALL-B-ALL/NHL
HOVON
Immunodeficiency-related
L3ALL
LMB
Sporadic form
T(8;14)
Tumor lysis syndrome
hyperCVAD
Journal
Current oncology reports
ISSN: 1534-6269
Titre abrégé: Curr Oncol Rep
Pays: United States
ID NLM: 100888967
Informations de publication
Date de publication:
06 03 2020
06 03 2020
Historique:
entrez:
8
3
2020
pubmed:
8
3
2020
medline:
13
7
2021
Statut:
epublish
Résumé
Burkitt's lymphoma and its leukemic form (Burkitt cell acute lymphoblastic leukemia) are a highly aggressive disease. We review the classification, clinical presentation, histology, cytogenetics, and the treatment of the disease. Burkitt's lymphoma might be associated with tumor lysis syndrome which is a potentially fatal complication that occurs spontaneously or upon initiation of chemotherapy. Major improvements were made in the treatment of pediatric and adults population using short-course dose-intensive chemotherapy regimens, usually 1 week after a prephase induction. Addition of Rituximab to chemotherapy has become a standard of care. Relapsed/refractory disease has a very poor prognosis and the benefit from autologous/allogeneic hematopoietic stem cell transplant remains uncertain. Rituximab-based short-course dose-intensive chemotherapy is the standard of care of Burkitt's lymphoma even in the immunodeficiency-related form.
Identifiants
pubmed: 32144513
doi: 10.1007/s11912-020-0898-8
pii: 10.1007/s11912-020-0898-8
doi:
Substances chimiques
Antigens, CD20
0
BCL6 protein, human
0
Proto-Oncogene Proteins c-bcl-6
0
Rituximab
4F4X42SYQ6
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
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