Right sinus of Valsalva aneurysm.

Aneurysm of right sinus of Valsalva Autopsy Cardiovascular disease Fatal arrhythmia Rare cardiac anomaly

Journal

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
ISSN: 1879-1336
Titre abrégé: Cardiovasc Pathol
Pays: United States
ID NLM: 9212060

Informations de publication

Date de publication:
Historique:
received: 15 10 2019
revised: 27 01 2020
accepted: 28 01 2020
pubmed: 8 3 2020
medline: 7 7 2020
entrez: 8 3 2020
Statut: ppublish

Résumé

Aneurysms in the sinuses of Valsalva (SVA) are the least frequent and occur due to a weakness in the aortic wall that forms part of the sinus. This causes dilatation and the formation of a blind pocket in one of the aortic sinuses (usually he right sinus and less frequently the posterior one). It may be congenital or acquired: in a congenital SVA, the condition is frequently associated with Marfan's syndrome or other connective tissue disorders; instead, acquired forms of sinus of Valsalva aneurysm are associated with infections (syphilis, bacterial endocarditis, and tuberculosis), atherosclerosis and medial cystic necrosis, traumatic and degenerative diseases, abuse of drugs or alcoholism. Despite SVA is a well-known anomaly, autopsy images or reviews of the condition are very uncommon. Indeed we report here a fatal case of SVA in a 58-year-old homeless man found dead on the street. The autopsy, performed to determine the cause of death, releaved a massive aneurysm (in excess of 4 cm) involving the right coronary sinus of the aorta. In this case, the aneurysm may be an accidental finding: in effect we found no tromboses inside the aneurysm and the ostium was not obstructed, therefore the cause of death could be attribuited to fatal arrhythmia.

Identifiants

pubmed: 32145675
pii: S1054-8807(20)30013-2
doi: 10.1016/j.carpath.2020.107209
pii:
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

107209

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Giorgia Farì (G)

Institute of Biochemistry and Clinical Biochemistry, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma-Università Cattolica Del Sacro Cuore, Roma, Italy.

Ilaria Pennacchia (I)

Area of Pathology, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Istituto di Anatomia Patologica, Università Cattolica Del Sacro Cuore, Rome, Italy.

Egidio Stigliano (E)

Area of Pathology, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Istituto di Anatomia Patologica, Università Cattolica Del Sacro Cuore, Rome, Italy.

Antonio Oliva (A)

Institute of Public Health, Section of Legal Medicine, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica Del Sacro Cuore, Italy.

Arnaldo Carbone (A)

Area of Pathology, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Istituto di Anatomia Patologica, Università Cattolica Del Sacro Cuore, Rome, Italy.

Vincenzo Arena (V)

Area of Pathology, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Istituto di Anatomia Patologica, Università Cattolica Del Sacro Cuore, Rome, Italy. Electronic address: vincenzo.arena@policlinicogemelli.it.

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Classifications MeSH