Toxicity of Metformin and Hypoglycemic Therapies.

Diabetes Mellitus, Type 2 / complications Dose-Response Relationship, Drug Drug Monitoring Humans Hypoglycemic Agents / adverse effects Metformin / adverse effects Renal Insufficiency, Chronic / etiology
Adverse effects Chronic kidney disease Diabetes mellitus Safety Toxicity

Journal

Advances in chronic kidney disease
ISSN: 1548-5609
Titre abrégé: Adv Chronic Kidney Dis
Pays: United States
ID NLM: 101209214

Informations de publication

Date de publication:
01 2020
Historique:
received: 29 07 2019
accepted: 01 08 2019
entrez: 10 3 2020
pubmed: 10 3 2020
medline: 13 1 2021
Statut: ppublish

Résumé

Metformin along with other antidiabetic medications provide benefit to patients in the treatment of type 2 diabetes mellitus, but caution is advised in certain scenarios to avoid toxicity in kidney disease. Renal dosing, monitoring of kidney function, and evaluating the risk of developing serious side effects are warranted with some agents. The available literature with regard to incidence of adverse events and toxicity of hypoglycemic therapies is reviewed.

Identifiants

DOI: 10.1053/j.ackd.2019.08.004 PMID: 32146997
pubmed: 32146997
pii: S1548-5595(19)30144-2
doi: 10.1053/j.ackd.2019.08.004
pii:
doi:

Substances chimiques

Hypoglycemic Agents 0
Metformin 9100L32L2N

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

18-30

Informations de copyright

Copyright © 2019 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Auteurs

Muhammad S Akhter (MS)

Mount Sinai Beth Israel/Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: saleem234@gmail.com.

Priyasha Uppal (P)

Mount Sinai Beth Israel, New York, NY.

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Classifications MeSH

questionsmedicales.fr › Maladies endocriniennes › Diabète › Diabète de type 2 › Toxicity of Metformin and Hypoglycemic Therapies.
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Toxicity of Metformin and Hypoglycemic Therapies.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Monitorage physiologique › Surveillance des médicaments › Toxicity of Metformin and Hypoglycemic Therapies.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Toxicity of Metformin and Hypoglycemic Therapies.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hypoglycémiants › Toxicity of Metformin and Hypoglycemic Therapies.
questionsmedicales.fr › Composés chimiques organiques › Amidines › Guanidines › Biguanides › Metformine › Toxicity of Metformin and Hypoglycemic Therapies.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Insuffisance rénale chronique › Toxicity of Metformin and Hypoglycemic Therapies.