TRAF5 Deficiency Ameliorates the Severity of Dextran Sulfate Sodium Colitis by Decreasing TRAF2 Expression in Nonhematopoietic Cells.


Journal

ImmunoHorizons
ISSN: 2573-7732
Titre abrégé: Immunohorizons
Pays: United States
ID NLM: 101708159

Informations de publication

Date de publication:
10 03 2020
Historique:
received: 24 01 2020
accepted: 20 02 2020
entrez: 12 3 2020
pubmed: 12 3 2020
medline: 20 11 2020
Statut: epublish

Résumé

TNFR-associated factor 5 (TRAF5) is a cytosolic adaptor protein and functions as an inflammatory regulator. However, the in vivo function of TRAF5 remains unclear, and how TRAF5 controls inflammatory responses in the intestine is not well understood. In this study, we found that intestinal epithelial cells from

Identifiants

pubmed: 32156688
pii: 4/3/129
doi: 10.4049/immunohorizons.2000007
doi:

Substances chimiques

Cytokines 0
TNF Receptor-Associated Factor 2 0
TNF Receptor-Associated Factor 5 0
TRAF2 protein, mouse 0
Dextran Sulfate 9042-14-2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

129-139

Commentaires et corrections

Type : ErratumIn

Informations de copyright

Copyright © 2020 The Authors.

Auteurs

Hai The Phung (HT)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

Hiroyuki Nagashima (H)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

Shuhei Kobayashi (S)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

Naoki Asano (N)

Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.

Tomoaki Machiyama (T)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan; and.

Tsuyoshi Sakurai (T)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

Shunichi Tayama (S)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

Atsuko Asao (A)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

Akira Imatani (A)

Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.

Takeshi Kawabe (T)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

Yuko Okuyama (Y)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

Naoto Ishii (N)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

Takanori So (T)

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan; tso@pha.u-toyama.ac.jp.
Laboratory of Molecular Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan.

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Classifications MeSH