Identification of Amoxicillin Crystals in Urine: a Case Report.
Journal
Clinical laboratory
ISSN: 1433-6510
Titre abrégé: Clin Lab
Pays: Germany
ID NLM: 9705611
Informations de publication
Date de publication:
01 Mar 2020
01 Mar 2020
Historique:
entrez:
13
3
2020
pubmed:
13
3
2020
medline:
17
12
2020
Statut:
ppublish
Résumé
The case concerns a 30-year-old woman in the 24th week of pregnancy presenting to the medical emergency room with fever and abdominal pain. Urine sediment microscopy revealed the presence of unknown needle-shaped crystals. Crystals identification was performed by Fourier-Transform Infrared Spectroscopy coupled to Attenuated Total Reflectance (FTIR-ATR). Amoxicillin crystals were verified with semiquantitative results of 87.7%. Drug-induced crystalluria is a frequent finding in urine examination and it may be asymptomatic. FTIR spectroscopy is a rapid and specific tool in identification of crystals and could be useful supporting renal disease diagnosis and monitoring drug therapy.
Sections du résumé
BACKGROUND
BACKGROUND
The case concerns a 30-year-old woman in the 24th week of pregnancy presenting to the medical emergency room with fever and abdominal pain. Urine sediment microscopy revealed the presence of unknown needle-shaped crystals.
METHODS
METHODS
Crystals identification was performed by Fourier-Transform Infrared Spectroscopy coupled to Attenuated Total Reflectance (FTIR-ATR).
RESULTS
RESULTS
Amoxicillin crystals were verified with semiquantitative results of 87.7%.
CONCLUSIONS
CONCLUSIONS
Drug-induced crystalluria is a frequent finding in urine examination and it may be asymptomatic. FTIR spectroscopy is a rapid and specific tool in identification of crystals and could be useful supporting renal disease diagnosis and monitoring drug therapy.
Identifiants
pubmed: 32162882
doi: 10.7754/Clin.Lab.2019.190606
doi:
Substances chimiques
Anti-Bacterial Agents
0
Amoxicillin
804826J2HU
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM