[The risk of re-identification when analyzing electronic health records: a critical appraisal and possible solutions].

Das Risiko von Re-Identifizierung bei der Auswertung medizinischer Routinedaten – Kritische Bewertung und Lösungsansätze.
Allgemeinmedizin Data anonymization Datenanonymisierung Datenschutz Electronic health records Elektronische Patientenakten Family practice Primärversorgung Privacy of patient data Quality of healthcare Qualitätssicherung in der medizinischen Versorgung Statistics and numerical data in primary healthcare Statistische Datengrundlagen der ambulanten

Journal

Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen
ISSN: 2212-0289
Titre abrégé: Z Evid Fortbild Qual Gesundhwes
Pays: Netherlands
ID NLM: 101477604

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 25 05 2019
revised: 14 11 2019
accepted: 15 01 2020
pubmed: 14 3 2020
medline: 6 5 2020
entrez: 14 3 2020
Statut: ppublish

Résumé

The use of primary care data gathered from electronic health records in local practices could be an important building block for the future of health services research. However, the risks and reservations associated with using this data for research purposes should not be underestimated. We show the data protection and privacy problems that may arise through secondary analysis of routine primary care data and describe the technical solutions that are available to address these concerns - as a trust-building measure. We screened 40 variables that are deemed important for documentation in the electronic health records of primary care physicians and rated the risk of patient re-identification when using these records from routine medical data for research purposes. The criteria used to rate the risk of re-identification were "expert perception" (inferences of a professional observer of phenotypical characteristics which are documented in the 40 variables), "researchable additional knowledge" (knowledge of characteristics of a person through publicly available information and social media networks), and "statistic frequency" according to diagnosis and medication statistics. Diagnoses and reasons for contacting a general practitioner can contain particularly identifiable characteristics such as "obesity" (ICD-10 E66) and "nicotine dependence" (F17). About half of all ICD codes documented in primary care fall below a critical threshold value in their absolute frequency; this is all the more problematic if diagnoses allow for re-identification due to phenotypical characteristics. Medication information holds little potential risk of re-identification of a person. However, the application of medications could be a source of re-identification, e. g., self-injections of insulin or use of inhalators. Information about times and dates are especially sensitive for the re-identification of a person. Sex and age of a patient generally pose no problems, except in the case of very young or very old individuals when these age groups are seldom represented in the practice. Routine health data are, in principle, sensitive data. Knowledge about the variables in primary care data gathered from electronic health records in local practices and the evaluation of this data allow us to more accurately estimate the risk of re-identification for the persons concerned. In particular, chronic diagnoses and/or diagnoses in long text, calendar dates for patient contacts and therapies bear a high risk of re-identification. Technical measures such as removing data, masking values and coding should make re-identification considerably more difficult. There will always be a remaining risk of re-identification which should be openly discussed to counteract concerns about a lack of data protection or a sweeping critique of digitization in healthcare.

Sections du résumé

BACKGROUND AND OBJECTIVES OBJECTIVE
The use of primary care data gathered from electronic health records in local practices could be an important building block for the future of health services research. However, the risks and reservations associated with using this data for research purposes should not be underestimated. We show the data protection and privacy problems that may arise through secondary analysis of routine primary care data and describe the technical solutions that are available to address these concerns - as a trust-building measure.
METHODS METHODS
We screened 40 variables that are deemed important for documentation in the electronic health records of primary care physicians and rated the risk of patient re-identification when using these records from routine medical data for research purposes. The criteria used to rate the risk of re-identification were "expert perception" (inferences of a professional observer of phenotypical characteristics which are documented in the 40 variables), "researchable additional knowledge" (knowledge of characteristics of a person through publicly available information and social media networks), and "statistic frequency" according to diagnosis and medication statistics.
RESULTS RESULTS
Diagnoses and reasons for contacting a general practitioner can contain particularly identifiable characteristics such as "obesity" (ICD-10 E66) and "nicotine dependence" (F17). About half of all ICD codes documented in primary care fall below a critical threshold value in their absolute frequency; this is all the more problematic if diagnoses allow for re-identification due to phenotypical characteristics. Medication information holds little potential risk of re-identification of a person. However, the application of medications could be a source of re-identification, e. g., self-injections of insulin or use of inhalators. Information about times and dates are especially sensitive for the re-identification of a person. Sex and age of a patient generally pose no problems, except in the case of very young or very old individuals when these age groups are seldom represented in the practice.
DISCUSSION CONCLUSIONS
Routine health data are, in principle, sensitive data. Knowledge about the variables in primary care data gathered from electronic health records in local practices and the evaluation of this data allow us to more accurately estimate the risk of re-identification for the persons concerned. In particular, chronic diagnoses and/or diagnoses in long text, calendar dates for patient contacts and therapies bear a high risk of re-identification. Technical measures such as removing data, masking values and coding should make re-identification considerably more difficult. There will always be a remaining risk of re-identification which should be openly discussed to counteract concerns about a lack of data protection or a sweeping critique of digitization in healthcare.

Identifiants

pubmed: 32165110
pii: S1865-9217(20)30003-9
doi: 10.1016/j.zefq.2020.01.002
pii:
doi:

Types de publication

Journal Article

Langues

ger

Sous-ensembles de citation

IM

Pagination

22-31

Informations de copyright

Copyright © 2019.

Auteurs

Johannes Hauswaldt (J)

Institut für Allgemeinmedizin, Universitätsmedizin Göttingen, Göttingen, Deutschland. Electronic address: johannes.hauswaldt@med.uni-goettingen.de.

Iris Demmer (I)

Institut für Allgemeinmedizin, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Stephanie Heinemann (S)

Institut für Allgemeinmedizin, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Wolfgang Himmel (W)

Institut für Allgemeinmedizin, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Eva Hummers (E)

Institut für Allgemeinmedizin, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Johannes Pung (J)

Institut für Medizinische Informatik, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Falk Schlegelmilch (F)

Institut für Allgemeinmedizin, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Johannes Drepper (J)

TMF - Technologie- und Methodenplattform für die vernetzte medizinische Forschung e.V., Berlin (TMF), Deutschland.

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