Does treatment guided by exhaled nitric oxide fraction improve outcomes in subgroups of children with asthma?

Adolescent Anti-Asthmatic Agents / therapeutic use Asthma / drug therapy Biomarkers / metabolism Breath Tests Child Female Forced Expiratory Volume Humans Kaplan-Meier Estimate Leukotriene Antagonists / therapeutic use Male Nitric Oxide / analysis Randomized Controlled Trials as Topic Treatment Outcome

Journal

The European respiratory journal
ISSN: 1399-3003
Titre abrégé: Eur Respir J
Pays: England
ID NLM: 8803460

Informations de publication

Date de publication:
05 2020
Historique:
received: 22 09 2019
accepted: 17 02 2020
pubmed: 14 3 2020
medline: 17 2 2021
entrez: 14 3 2020
Statut: epublish

Résumé

Exhaled nitric oxide fraction ( An individual patient data analysis was performed using data from seven randomised clinical trials (RCTs) which used Data were available in 1112 RCT participants. Among those not treated with leukotriene receptor antagonists (LTRA), but not among those who were treated with LTRA, Asthma treatment guided by

Identifiants

DOI: 10.1183/13993003.01879-2019 PMID: 32165403
pubmed: 32165403
pii: 13993003.01879-2019
doi: 10.1183/13993003.01879-2019
pii:
doi:

Substances chimiques

Anti-Asthmatic Agents 0
Biomarkers 0
Leukotriene Antagonists 0
Nitric Oxide 31C4KY9ESH

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright ©ERS 2020.

Déclaration de conflit d'intérêts

Conflict of interest: S. Fielding has nothing to disclose. Conflict of interest: M. Pijnenburg has nothing to disclose. Conflict of interest: J. de Jongste has nothing to disclose. Conflict of interest: K. Pike has nothing to disclose. Conflict of interest: G. Roberts has nothing to disclose. Conflict of interest: H. Petsky has nothing to disclose. Conflict of interest: A.B. Chang reports grants (project, Centre for Research Excellence and practitioner fellowship) from the National Health and Medical Research Council, Australia during the conduct of the study; and other potential conflict from being an author in UpToDate and USA Chest Chronic Cough Guidelines outside the submitted work. Conflict of interest: M. Fritsch has nothing to disclose. Conflict of interest: T. Frischer has nothing to disclose. Conflict of interest: S.J. Szefler has nothing to disclose. Conflict of interest: P. Gergen has nothing to disclose. Conflict of interest: F. Vermeulen has nothing to disclose. Conflict of interest: R. Vael has nothing to disclose. Conflict of interest: S.S. Turner has nothing to disclose.

Auteurs

Shona S Fielding (SS)

Medical Statistics Team, Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.

Marielle Pijnenburg (M)

Dept of Paediatric Respiratory Medicine and Allergology, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands.

Johan de Jongste (J)

Dept of Paediatric Respiratory Medicine and Allergology, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands.

Katherine Pike (K)

Clinical and Experimental Science Academic Unit, University of Southampton, Southampton, UK.
Respiratory Critical Care and Anaesthesia Group, Institute of Child Health, University College London, London, UK.

Graham Roberts (G)

Clinical and Experimental Science Academic Unit, University of Southampton, Southampton, UK.

Helen Petsky (H)

School of Nursing and Midwifery, Griffith University, Menzies Health Institute Queensland, Brisbane, Australia.

Anne B Chang (AB)

Dept of Respiratory and Sleep Medicine, Queensland Children's Hospital, Queensland University of Technology, Brisbane, Australia.
Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia.

Maria Fritsch (M)

University Children's Hospital, Vienna, Austria.

Thomas Frischer (T)

University Children's Hospital, Vienna, Austria.

Stanley J Szefler (SJ)

Breathing Institute, Children's Hospital Colorado, Dept of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.

Peter Gergen (P)

National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.

Francoise Vermeulen (F)

Pediatric Dept, Hôpital Erasme, Université Libre de Bruxelles (U.L.B.), Brussels, Belgium.

Robin Vael (R)

Dept of Paediatrics, Antwerp University Hospital, Antwerp, Belgium.

Steve S Turner (SS)

Child Health, University of Aberdeen, Aberdeen, UK s.w.turner@abdn.ac.uk.
ORCID: 0000-0001-8393-5060

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adolescent › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents de l'appareil respiratoire › Antiasthmatiques › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Maladies du système immunitaire › Hypersensibilité › Hypersensibilité immédiate › Hypersensibilité respiratoire › Asthme › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Tests d'analyse de l'haleine › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques respiratoires › Ventilation pulmonaire › Volume expiratoire maximal par seconde › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de survie › Estimation de Kaplan-Meier › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hormones, substituts d'hormones et antagonistes d'hormones › Antihormones › Antagonistes des leucotriènes › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Oxydes d'azote › Monoxyde d'azote › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études cliniques comme sujet › Essais cliniques comme sujet › Essais cliniques contrôlés comme sujet › Essais contrôlés randomisés comme sujet › Does treatment guided by exhaled nitric oxide...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Qualité des soins de santé › Mécanismes d'évaluation des soins de santé › Évaluation des résultats et des processus en soins de santé › Évaluation de résultat (soins) › Résultat thérapeutique › Does treatment guided by exhaled nitric oxide...