Disinfection of contaminated metal implants with an Er:YAG laser.
Er:YAG laser
biofilm removal, DAIR
implant-related infection
laser disinfection
pin-tract infection
Journal
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
ISSN: 1554-527X
Titre abrégé: J Orthop Res
Pays: United States
ID NLM: 8404726
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
13
01
2020
revised:
04
03
2020
accepted:
06
03
2020
pubmed:
14
3
2020
medline:
2
2
2021
entrez:
14
3
2020
Statut:
ppublish
Résumé
Infections related to orthopedic procedures are considered particularly severe when implantation materials are used, because effective treatments for biofilm removal are lacking. In this study, the relatively new approach for infection control by using an erbium:yttrium-aluminum-garnet (Er:YAG) laser was tested. This laser vaporizes all water containing cells in a very effective, precise, and predictable manner and results in only minimal thermal damage. For preliminary testing, 42 steel plates and 42 pins were seeded with mixed cultures. First, the minimally necessary laser energy for biofilm removal was determined. Subsequently, the effectiveness of biofilm removal with the Er:YAG laser and the cleansing of the metal implants with octenidine-soaked gauze was compared. Then, we compared the effectiveness of biofilm removal on 207 steel pins from 41 patients directly after explantation. Sonication and scanning electron microscopy were used for analysis. Laser fluences exceeding 2.8 J/cm
Identifiants
pubmed: 32167192
doi: 10.1002/jor.24662
pmc: PMC7687249
doi:
Types de publication
Clinical Trial
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2464-2473Informations de copyright
© 2020 The Authors. Journal of Orthopaedic Research® published by Wiley Periodicals LLC on behalf of Orthopaedic Research Society.
Références
J Bone Joint Surg Am. 1984 Sep;66(7):1092-8
pubmed: 6384221
N Engl J Med. 2004 Oct 14;351(16):1645-54
pubmed: 15483283
Clin Microbiol Infect. 2013 Feb;19(2):181-6
pubmed: 22264335
N Engl J Med. 2007 Aug 16;357(7):654-63
pubmed: 17699815
Acta Orthop. 2007 Jun;78(3):299-308
pubmed: 17611841
ASAIO J. 1992 Jul-Sep;38(3):M174-8
pubmed: 1457842
Plast Reconstr Surg. 2012 Mar;129(3):602e-604e
pubmed: 22374043
J Orthop Trauma. 1999 Feb;13(2):98-101
pubmed: 10052783
Antimicrob Agents Chemother. 1985 Dec;28(6):786-90
pubmed: 3909955
Orthop Traumatol Surg Res. 2010 Apr;96(2):124-32
pubmed: 20417910
Antimicrob Agents Chemother. 1983 Mar;23(3):379-84
pubmed: 6847170
Arch Dermatol. 1999 Apr;135(4):444-54
pubmed: 10206052
Acta Orthop. 2012 Jun;83(3):299-304
pubmed: 22616742
Biomaterials. 2002 Feb;23(3):887-92
pubmed: 11771707
J Bone Joint Surg Am. 2003;85-A Suppl 4:129-31
pubmed: 14652404
Science. 1987 Sep 25;237(4822):1588-95
pubmed: 3629258
Bone. 2003 May;32(5):521-31
pubmed: 12753868
J Biomed Mater Res. 2000 Sep;53(5):600-4
pubmed: 10984710
Orthopedics. 1991 Mar;14(3):305-8
pubmed: 2020629
J Trauma. 1993 Nov;35(5):776-85
pubmed: 8230346
Annu Rev Microbiol. 1987;41:435-64
pubmed: 3318676
J Mater Sci Mater Med. 2007 Apr;18(4):565-75
pubmed: 17546415
Arch Orthop Trauma Surg. 1994;113(5):271-5
pubmed: 7946818
J Bone Joint Surg Am. 1989 Jul;71(6):835-8
pubmed: 2745479
Scand J Plast Reconstr Surg. 1984;18(3):261-8
pubmed: 6549359
Appl Environ Microbiol. 2009 Jun;75(12):4089-92
pubmed: 19376913
J Antimicrob Chemother. 2004 Dec;54(6):1019-24
pubmed: 15537697
Thromb Haemost. 2013 May;109(5):869-77
pubmed: 23494019
Injury. 2010 Feb;41(2):147-50
pubmed: 19647820
Antimicrob Agents Chemother. 1990 Sep;34(9):1666-71
pubmed: 2126686
Clin Orthop Relat Res. 1997 Mar;(336):205-15
pubmed: 9060507
J Mater Sci Mater Med. 2003 Jun;14(6):521-9
pubmed: 15348436
J Orthop Res. 2020 Nov;38(11):2464-2473
pubmed: 32167192
Clin Microbiol Rev. 2014 Apr;27(2):302-45
pubmed: 24696437
Lasers Surg Med. 1989;9(4):314-26
pubmed: 2761327
Clin Orthop Relat Res. 1983 Nov;(180):109-16
pubmed: 6627782
BMC Microbiol. 2009 Apr 22;9:76
pubmed: 19386094
J Clin Microbiol. 1999 Jun;37(6):1771-6
pubmed: 10325322
FEMS Microbiol Rev. 2003 Jun;27(2-3):341-53
pubmed: 12829274
Science. 1999 May 21;284(5418):1318-22
pubmed: 10334980
J Hosp Infect. 2003 Oct;55(2):108-15
pubmed: 14529634
Future Microbiol. 2014;9(8):987-1007
pubmed: 25302955
Lasers Surg Med. 1997;20(3):242-7
pubmed: 9138252