Fighting Against Promoter DNA Hyper-Methylation: Protective Histone Modification Profiles of Stress-Resistant Intestinal Stem Cells.
DNA damage
computational modeling
histone methylation
irradiation
loss of Msh2 function
promoter DNA hyper-methylation
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
12 Mar 2020
12 Mar 2020
Historique:
received:
07
02
2020
revised:
27
02
2020
accepted:
02
03
2020
entrez:
18
3
2020
pubmed:
18
3
2020
medline:
2
12
2020
Statut:
epublish
Résumé
Aberrant DNA methylation in stem cells is a hallmark of aging and tumor development. Recently, we have suggested that promoter DNA hyper-methylation originates in DNA repair and that even successful DNA repair might confer this kind of epigenetic long-term change. Here, we ask for interrelations between promoter DNA methylation and histone modification changes observed in the intestine weeks after irradiation and/or following
Identifiants
pubmed: 32178409
pii: ijms21061941
doi: 10.3390/ijms21061941
pmc: PMC7139626
pii:
doi:
Substances chimiques
Histones
0
histone H3 trimethyl Lys4
0
DNA
9007-49-2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Bundesministerium für Bildung und Forschung
ID : 031A312
Organisme : Bundesministerium für Bildung und Forschung
ID : 01ZX1304A
Organisme : Volkswagen Foundation
ID : Lichtenberg program
Organisme : Deutsche Forschungsgemeinschaft
ID : Clinical Research Unit KFO286
Organisme : Deutsche Forschungsgemeinschaft
ID : Collaborative Research Centre SFB1399
Références
Environ Res. 2016 Apr;146:10-7
pubmed: 26708527
Mol Cell. 2013 Jan 24;49(2):359-367
pubmed: 23177740
Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):466-71
pubmed: 22190486
Gastroenterology. 2012 Nov;143(5):1266-1276
pubmed: 22841781
Aging Cell. 2014 Apr;13(2):320-8
pubmed: 24428552
Nat Genet. 2007 Feb;39(2):232-6
pubmed: 17200670
Curr Opin Genet Dev. 2008 Apr;18(2):109-15
pubmed: 18339538
Gastroenterology. 2004 Mar;126(3):796-808
pubmed: 14988834
Nucleic Acids Res. 2017 Sep 29;45(17):9889-9900
pubmed: 28973438
Mol Cancer Res. 2005 Oct;3(10):553-61
pubmed: 16254189
Genes Dev. 2017 May 15;31(10):959-972
pubmed: 28607180
Nat Cell Biol. 2015 Sep;17(9):1158-68
pubmed: 26237645
Epigenetics. 2017;12(10):886-896
pubmed: 28758855
Nat Commun. 2017 Jun 26;8(1):36
pubmed: 28652613
Genome Res. 2010 Apr;20(4):440-6
pubmed: 20219944
Development. 2016 Oct 15;143(20):3639-3649
pubmed: 27802133
Mol Cell. 2018 Aug 16;71(4):581-591.e5
pubmed: 30057196
Epigenetics. 2009 Aug 16;4(6):404-14
pubmed: 19717977
Environ Pollut. 2018 Mar;234:935-942
pubmed: 29253833
Phys Biol. 2013 Apr;10(2):026006
pubmed: 23481318
Stem Cell Reports. 2018 Aug 14;11(2):578-592
pubmed: 30078558
J Biotechnol. 2010 Sep 1;149(3):98-114
pubmed: 20156493
PLoS Genet. 2009 Aug;5(8):e1000602
pubmed: 19680444
Sci Rep. 2016 Sep 15;6:33222
pubmed: 27629060
Nucleic Acids Res. 2010 Aug;38(15):4958-69
pubmed: 20385584
Epigenetics. 2014 Apr;9(4):546-56
pubmed: 24434851
Genes (Basel). 2018 Jan 05;9(1):
pubmed: 29303998
Nature. 2007 Aug 9;448(7154):714-7
pubmed: 17687327
Cell. 2010 Oct 1;143(1):134-44
pubmed: 20887898
Cell. 2018 Nov 15;175(5):1307-1320.e22
pubmed: 30392957
Int J Radiat Biol. 1994 Jan;65(1):71-8
pubmed: 7905913
Cell Biosci. 2014 Aug 19;4:46
pubmed: 25949795
Nature. 2007 Aug 2;448(7153):553-60
pubmed: 17603471
Nucleic Acids Res. 2016 Oct 14;44(18):8682-8692
pubmed: 27288448
Genome Biol. 2014 Feb 03;15(2):R24
pubmed: 24490752
Nat Commun. 2016 Aug 17;7:12514
pubmed: 27530917
Science. 2011 Dec 9;334(6061):1420-4
pubmed: 22075725
Nucleic Acids Res. 2017 Jun 2;45(10):5770-5784
pubmed: 28334816
J R Soc Interface. 2016 Aug;13(121):
pubmed: 27534699
Mol Cell. 2018 Oct 18;72(2):239-249.e5
pubmed: 30146316
Nature. 2007 Oct 25;449(7165):1003-7
pubmed: 17934449
Nat Rev Cancer. 2014 Dec;14(12):786-800
pubmed: 25568919
Cell Stem Cell. 2013 Mar 7;12(3):298-303
pubmed: 23415913
PLoS Genet. 2008 Aug 15;4(8):e1000155
pubmed: 18704159
Genome Biol. 2013;14(10):R115
pubmed: 24138928
Clin Epigenetics. 2019 Apr 27;11(1):65
pubmed: 31029155
Transl Cancer Res. 2016 Dec;5(6):707-724
pubmed: 28690977
Clin Epigenetics. 2017 Sep 22;9:104
pubmed: 29018507
Nat Genet. 2015 May;47(5):479-85
pubmed: 25848754
PLoS One. 2015 Jun 04;10(6):e0128555
pubmed: 26042422
Mol Cell. 2015 Nov 19;60(4):584-96
pubmed: 26590716