Phaeochromocytoma presenting as Takotsubo cardiomyopathy.


Journal

Clinical medicine (London, England)
ISSN: 1473-4893
Titre abrégé: Clin Med (Lond)
Pays: England
ID NLM: 101092853

Informations de publication

Date de publication:
03 2020
Historique:
entrez: 20 3 2020
pubmed: 20 3 2020
medline: 15 5 2021
Statut: ppublish

Résumé

We report a case of a 72-year-old woman who presented with ST-elevation myocardial infarction (STEMI). However, coronary angiography showed unobstructed arteries while echocardiography (ECHO) showed severe left ventricular (LV) apical hypokinesia with ejection fraction (EF) of 25-30%. Seven months later she presented with a transient ischaemic attack and a repeat ECHO showed a normal EF.A few months later, she was diagnosed with breast cancer and as part of staging procedure, an incidental left adrenal mass was identified. This was biochemically confirmed as phaeochromocytoma (PY) and she underwent laparoscopic adrenalectomy.PY is a rare catecholamine secreting tumour arising from adrenomedullary chromaffin cells. Excessive catecholamine-induced stimulation can present as transient, reversible cardiomyopathy similar to Takotsubo cardiomyopathy and cerebrovascular events. The diagnosis of PY is often delayed but it is important to recognize PY as a cause of reversible cardiomyopathy. Early intervention is essential to improve mortality from cardiovascular and cerebrovascular complications.

Identifiants

pubmed: 32188661
pii: 20/2/212
doi: 10.7861/clinmed.2019-0494
pmc: PMC7081805
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

212-214

Informations de copyright

© Royal College of Physicians 2020. All rights reserved.

Références

Tex Heart Inst J. 2019 Apr 1;46(2):124-127
pubmed: 31236077
Medicine (Baltimore). 2015 Dec;94(50):e2198
pubmed: 26683930
Int J Cardiol. 2011 Dec 15;153(3):241-8
pubmed: 21474192
Int J Cardiol. 2017 Dec 15;249:319-323
pubmed: 29121733
Tex Heart Inst J. 2007;34(2):244-6
pubmed: 17622380

Auteurs

Oluwatosin Kayode (O)

Withybush General Hospital, Haverfordwest, UK tosinod2001@yahoo.co.uk.

Paul Underwood (P)

Withybush General Hospital, Haverfordwest, UK.

Ravi Dissanayake (R)

Withybush General Hospital, Haverfordwest, UK.

David Scott-Coombes (D)

University Hospital of Wales Healthcare NHS Trust, Cardiff, UK.

Subramaniam Nagasayi (S)

Withybush General Hospital, Haverfordwest, UK.

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Classifications MeSH