Matter-wave interference of a native polypeptide.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
19 03 2020
19 03 2020
Historique:
received:
10
10
2019
accepted:
26
02
2020
entrez:
21
3
2020
pubmed:
21
3
2020
medline:
14
7
2020
Statut:
epublish
Résumé
The de Broglie wave nature of matter is a paradigmatic example of quantum physics and it has been exploited in precision measurements of forces and fundamental constants. However, matter-wave interferometry has remained an outstanding challenge for natural polypeptides, building blocks of life, which are fragile and difficult to handle. Here, we demonstrate the wave nature of gramicidin, a natural antibiotic composed of 15 amino acids. Its center of mass is delocalized over more than 20 times the molecular size in our time-domain Talbot-Lau interferometer. We compare the observed interference fringes with a model that includes both a rigorous treatment of the peptide's quantum wave nature as well as a quantum chemical assessment of its optical properties to distinguish our result from classical predictions. The realization of quantum optics with this prototypical biomolecule paves the way for quantum-assisted measurements on a large class of biologically relevant molecules.
Identifiants
pubmed: 32193414
doi: 10.1038/s41467-020-15280-2
pii: 10.1038/s41467-020-15280-2
pmc: PMC7081299
doi:
Substances chimiques
Peptides
0
Gramicidin
1405-97-6
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
1447Références
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