Expression of molecules of the Wnt pathway and of E-cadherin in the etiopathogenesis of human thymomas.
E-cadherin
Wnt
axin2
thymoma
β-catenin
Journal
Oncology letters
ISSN: 1792-1074
Titre abrégé: Oncol Lett
Pays: Greece
ID NLM: 101531236
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
04
08
2019
accepted:
10
12
2019
entrez:
21
3
2020
pubmed:
21
3
2020
medline:
21
3
2020
Statut:
ppublish
Résumé
The molecular pathogenesis of thymoma remains largely unknown. It has been recently demonstrated, that activation of Wnt signaling pathway leads to increased incidence of thymoma in murine models. The present study investigated the activation of molecules of the Wnt signaling pathway in human thymoma. A total of 112 thymoma cases with complete clinical and follow-up data and 8 controls were included in the present study. Patients with thymoma and controls were examined immunohistochemically for β-catenin and E-cadherin. The mRNA expression levels of
Identifiants
pubmed: 32194741
doi: 10.3892/ol.2020.11343
pii: OL-0-0-11343
pmc: PMC7039126
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2413-2421Informations de copyright
Copyright: © Vodicka et al.
Références
Am J Pathol. 2001 Nov;159(5):1853-60
pubmed: 11696445
J Thorac Oncol. 2010 Oct;5(10 Suppl 4):S291-5
pubmed: 20859122
J Cell Biochem. 2014 Aug;115(8):1351-61
pubmed: 24610469
Genetics. 2014 Aug;197(4):1285-302
pubmed: 24931405
J Natl Cancer Inst. 2017 Aug 1;109(8):
pubmed: 28423402
Blood. 2007 Mar 1;109(5):1857-61
pubmed: 17105812
Cancer Res. 2003 Jul 1;63(13):3708-15
pubmed: 12839963
J Biosci. 2017 Dec;42(4):695-707
pubmed: 29229887
Eur J Immunol. 2003 Jul;33(7):1949-56
pubmed: 12884861
Ann Oncol. 2015 Sep;26 Suppl 5:v40-55
pubmed: 26314779
Cold Spring Harb Perspect Biol. 2013 Jan 01;5(1):a007898
pubmed: 23169527
J Immunol. 2009 Mar 1;182(5):2997-3007
pubmed: 19234195
J Pathol. 1998 Feb;184(2):207-11
pubmed: 9602713
Ann Thorac Surg. 2002 Mar;73(3):933-7
pubmed: 11899204
J Thorac Oncol. 2015 Sep;10(9):1240-1242
pubmed: 26291007
N Engl J Med. 1993 Sep 30;329(14):987-94
pubmed: 8141877
Anticancer Res. 2015 Feb;35(2):669-76
pubmed: 25667444
Clin Chem. 2001 Feb;47(2):195-201
pubmed: 11159766
J Pediatr. 2005 Aug;147(2):263-6
pubmed: 16126064
J Thorac Oncol. 2014 Jul;9(7):1018-1022
pubmed: 24926546
Immunity. 2013 Aug 22;39(2):298-310
pubmed: 23954131
Genes Cells. 1998 Jun;3(6):395-403
pubmed: 9734785
Cancer Metastasis Rev. 2018 Mar;37(1):159-172
pubmed: 29318445
J Thorac Oncol. 2010 Oct;5(10 Suppl 4):S286-90
pubmed: 20859121
Zhongguo Fei Ai Za Zhi. 2014 Feb;17(2):75-81
pubmed: 24581156
Ann Oncol. 2018 Mar 1;29(3):544-562
pubmed: 29194473
Tumour Biol. 2012 Dec;33(6):1871-9
pubmed: 22833212
Int J Cancer. 2003 Jul 1;105(4):546-51
pubmed: 12712448
Nat Rev Immunol. 2008 Aug;8(8):581-93
pubmed: 18617885
J Thorac Oncol. 2014 Sep;9(9 Suppl 2):S143-7
pubmed: 25396312
Nat Rev Immunol. 2013 Nov;13(11):831-8
pubmed: 24052146
Oncotarget. 2015 Jun 10;6(16):13978-93
pubmed: 26101855
Methods. 2001 Dec;25(4):402-8
pubmed: 11846609
Tissue Barriers. 2017 Jul 3;5(3):e1356900
pubmed: 28783415
J Biol Chem. 2001 Apr 13;276(15):12301-9
pubmed: 11121423
Eur J Cardiothorac Surg. 2014 Sep;46(3):361-8
pubmed: 24482389
J Cancer Res Clin Oncol. 2019 Jan;145(1):109-116
pubmed: 30328513