Treatment Outcomes of Incidental Intracranial Meningiomas: Results from the IMPACT Cohort.
Activities of Daily Living
Aged
Brain Neoplasms
/ pathology
Cohort Studies
Conservative Treatment
Disease Progression
Follow-Up Studies
Humans
Incidental Findings
Male
Meningioma
/ pathology
Middle Aged
Neurosurgical Procedures
Postoperative Complications
/ epidemiology
Retrospective Studies
Treatment Outcome
Asymptomatic
Incidental
Meningioma
Radiotherapy
Surgery
Journal
World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
21
11
2019
revised:
09
03
2020
accepted:
10
03
2020
pubmed:
23
3
2020
medline:
29
8
2020
entrez:
23
3
2020
Statut:
ppublish
Résumé
Incidental findings such as meningioma are becoming increasingly prevalent. There is no consensus on the optimal management of these patients. The aim of this study was to examine the outcomes of patients diagnosed with an incidental meningioma who were treated with surgery or radiotherapy. Single-center retrospective cohort study of adult patients diagnosed with an incidental intracranial meningioma (2007-2015). Outcomes recorded were postintervention morbidity, histopathologic diagnosis, and treatment response. Out of 441 patients, 44 underwent treatment. Median age at intervention was 56.1 years (interquartile range [IQR], 49.6-66.5); patients included 35 women and 9 men. The main indication for imaging was headache (25.9%). Median meningioma volume was 4.55 cm The morbidity after treatment of incidental intracranial meningioma is not negligible. Considering most operated tumors are WHO grade 1, treatment should be reserved for those manifesting symptoms or demonstrating substantial growth on radiologic surveillance.
Sections du résumé
BACKGROUND
Incidental findings such as meningioma are becoming increasingly prevalent. There is no consensus on the optimal management of these patients. The aim of this study was to examine the outcomes of patients diagnosed with an incidental meningioma who were treated with surgery or radiotherapy.
METHODS
Single-center retrospective cohort study of adult patients diagnosed with an incidental intracranial meningioma (2007-2015). Outcomes recorded were postintervention morbidity, histopathologic diagnosis, and treatment response.
RESULTS
Out of 441 patients, 44 underwent treatment. Median age at intervention was 56.1 years (interquartile range [IQR], 49.6-66.5); patients included 35 women and 9 men. The main indication for imaging was headache (25.9%). Median meningioma volume was 4.55 cm
CONCLUSIONS
The morbidity after treatment of incidental intracranial meningioma is not negligible. Considering most operated tumors are WHO grade 1, treatment should be reserved for those manifesting symptoms or demonstrating substantial growth on radiologic surveillance.
Identifiants
pubmed: 32200011
pii: S1878-8750(20)30529-5
doi: 10.1016/j.wneu.2020.03.060
pii:
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e725-e735Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.