Oncological and Surgical Outcomes of Patients Treated by Transoral CO
Adult
Aged
Aged, 80 and over
Carbon Dioxide
Carcinoma, Squamous Cell
/ mortality
Disease-Free Survival
Feasibility Studies
Female
Glottis
/ surgery
Humans
Laryngeal Neoplasms
/ mortality
Laryngoscopy
/ methods
Lasers, Gas
/ therapeutic use
Male
Middle Aged
Retrospective Studies
Survival Rate
Treatment Outcome
cancer
exposure
fold
glottic
laryngeal
margin
transoral laser microsurgery
vocal
Journal
Ear, nose, & throat journal
ISSN: 1942-7522
Titre abrégé: Ear Nose Throat J
Pays: United States
ID NLM: 7701817
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
pubmed:
25
3
2020
medline:
24
8
2021
entrez:
25
3
2020
Statut:
ppublish
Résumé
To investigate the feasibility and the outcomes of transoral laser CO Retrospective chart review of patients treated by TLM cordectomy in a single European University Hospital for early-stage vocal fold SCCs (Tis, T1a, T1b, and T2). The following TLM outcomes were studied regarding the tumor size (Tis and T1a vs T1b and T2) and the margin status (negative vs positive/suspicious): patient position; type of laryngoscope; requirement to external counter pressure; resection of supraglottic structures (eg, ventricular band, epiglottic petiole, and suprahyoid epiglottis); pre- and postoperative complications; overall survival; disease-specific survival (DSS); and disease-free survival (DFS). A total of 148 patients were included. The TLM was realized in 95.3% of cases. External counter pressure, partial, or total vestibulectomy were necessary in 65.9%, 57.4%, and 4.2% of cases, respectively. A resection of the epiglottic petiole was required in 24.8% of cases. The realization of both epiglottis petiole resection and vestibulectomies were significantly higher in patients with T2 and T1b SCCs compared to those with T1a and Tis SCCs ( The exposure of glottis is possible in 95% of cases of early-stage vocal cord SCC but requires the use of several additional surgical procedures, especially for anterior commissure SCCs. The SCC involvement of the vocal fold anterior commissure is associated with lower DSS, DFS, and laryngeal preservation rate.
Identifiants
pubmed: 32204623
doi: 10.1177/0145561320911486
doi:
Substances chimiques
Carbon Dioxide
142M471B3J
Types de publication
Evaluation Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM