Surgical site infection caused by Aeromonas hydrophila presenting as necrotizing soft tissue infection after esophagectomy.
Abdominal Wall
/ microbiology
Aeromonas hydrophila
/ isolation & purification
Aged
Debridement
Esophageal Neoplasms
/ surgery
Esophagectomy
/ adverse effects
Gram-Negative Bacterial Infections
/ diagnosis
Humans
Male
Necrosis
/ diagnosis
Severity of Illness Index
Surgical Wound Infection
/ diagnosis
Thoracoscopy
/ adverse effects
Aeromonas hydrophila
metalloprotease
necrotizing soft tissue infection
surgical site infection
virulence factor
Journal
The Journal of dermatology
ISSN: 1346-8138
Titre abrégé: J Dermatol
Pays: England
ID NLM: 7600545
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
04
02
2020
accepted:
24
02
2020
pubmed:
25
3
2020
medline:
16
3
2021
entrez:
25
3
2020
Statut:
ppublish
Résumé
Several virulence factors of Aeromonas such as hemolysin, proteases and lipases have been characterized. The relationship between these virulence factors and disease remains unclear. A 71-year-old man underwent thoracoscopic esophagectomy, lymph node dissection and Roux-en-Y reconstruction for esophageal cancer. On postoperative day 1, redness around the wound on the thoracic abdominal wall gradually enlarged and necrosis became apparent with septic shock. Necrotizing soft tissue infection was suspected and emergency surgical debridement was performed. Blood and wound cultures were positive for Aeromonas hydrophila. The strain was found to have hemolytic activity, proteolytic activity and extremely high elastolytic activity. In addition, the strain actively produced elastolytic metalloprotease, which may contribute to extensive tissue necrosis.
Identifiants
pubmed: 32207545
doi: 10.1111/1346-8138.15323
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
673-676Informations de copyright
© 2020 Japanese Dermatological Association.
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