Health risk assessment to dioxins, furans and PCBs in young children: The first French evaluation.
Animals
Child, Preschool
Cross-Sectional Studies
Dibenzofurans
/ analysis
Dibenzofurans, Polychlorinated
/ analysis
Diet
Dioxins
/ analysis
Fishes
Food Contamination
/ analysis
France
Furans
/ analysis
Humans
Infant
Infant Food
/ analysis
Milk
No-Observed-Adverse-Effect Level
Polychlorinated Biphenyls
/ analysis
Polychlorinated Dibenzodioxins
/ analysis
Risk Assessment
Contaminants
Exposure assessment
PCDD/F and PCBs
Population exposure
Risk characterization
Total diet study
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
ISSN: 1873-6351
Titre abrégé: Food Chem Toxicol
Pays: England
ID NLM: 8207483
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
30
11
2019
revised:
16
03
2020
accepted:
17
03
2020
pubmed:
27
3
2020
medline:
26
1
2021
entrez:
27
3
2020
Statut:
ppublish
Résumé
A total diet study (TDS) was conducted between 2010 and 2016 to characterize the health risk related to chemical residues in food of French not breastfed children under three years of age (infant TDS). Among the targeted substances, polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) have been characterized as they accumulate through the food chain, especially in lipid-rich food items, and because they have been associated with a number of adverse effects in humans. Food samples (n = 180) were collected to be representative of the dioxins and PCB exposure through the whole diet of non-breastfed children from 1 to 36 months old and prepared as consumed (including cooking) prior to analysis. Dietary exposure was then assessed for 705 representative children under 3 years of age based on their food consumptions recorded through a 3-consecutive-days record. Levels of PCDD/Fs and PCBs in infant food were lower than those observed in common food, leading to significant differences in exposure according to age groups. Mean exposures to PCDD/Fs ranged from 0.22 to 0.44 pg TEQ
Identifiants
pubmed: 32209356
pii: S0278-6915(20)30180-0
doi: 10.1016/j.fct.2020.111292
pii:
doi:
Substances chimiques
Dibenzofurans
0
Dibenzofurans, Polychlorinated
0
Dioxins
0
Furans
0
Polychlorinated Dibenzodioxins
0
Polychlorinated Biphenyls
DFC2HB4I0K
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
111292Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.