Area Under the Expiratory Flow-Volume Curve (AEX): Assessing Bronchodilator Responsiveness.
Area under flow–volume curve
Bronchodilator response
Lung function
Lung volumes
Spirometry
Journal
Lung
ISSN: 1432-1750
Titre abrégé: Lung
Pays: United States
ID NLM: 7701875
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
07
01
2020
accepted:
11
03
2020
pubmed:
27
3
2020
medline:
5
8
2021
entrez:
27
3
2020
Statut:
ppublish
Résumé
Area under expiratory flow-volume curve (AEX) is a useful spirometric tool in stratifying respiratory impairment. The AEX approximations based on isovolumic flows can be used with reasonable accuracy when AEX is unavailable. We assessed here pre- to post-bronchodilator (BD) variability of AEX The BD response was assessed in 4330 subjects by changes in FEV Using standard BD criteria, 24% of subjects had a positive response. Using the new BD response categories, only 23% of subjects had a negative response; 45% minimal, 18% mild, 9% moderate, and 5% had a marked BD response. Mean percent change of the square root AEX Mean pre- to post-BD variability of AEX
Sections du résumé
BACKGROUND
Area under expiratory flow-volume curve (AEX) is a useful spirometric tool in stratifying respiratory impairment. The AEX approximations based on isovolumic flows can be used with reasonable accuracy when AEX is unavailable. We assessed here pre- to post-bronchodilator (BD) variability of AEX
METHODS
The BD response was assessed in 4330 subjects by changes in FEV
RESULTS
Using standard BD criteria, 24% of subjects had a positive response. Using the new BD response categories, only 23% of subjects had a negative response; 45% minimal, 18% mild, 9% moderate, and 5% had a marked BD response. Mean percent change of the square root AEX
CONCLUSIONS
Mean pre- to post-BD variability of AEX
Identifiants
pubmed: 32211978
doi: 10.1007/s00408-020-00345-2
pii: 10.1007/s00408-020-00345-2
pmc: PMC7242267
doi:
Substances chimiques
Bronchodilator Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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