Reliability of Intraoperative Monitoring in Patients with a Preexisting Motor Deficit: Case Report and Literature Review.


Journal

Journal of neurological surgery. Part A, Central European neurosurgery
ISSN: 2193-6323
Titre abrégé: J Neurol Surg A Cent Eur Neurosurg
Pays: Germany
ID NLM: 101580767

Informations de publication

Date de publication:
Jul 2021
Historique:
pubmed: 30 3 2020
medline: 23 7 2021
entrez: 30 3 2020
Statut: ppublish

Résumé

 The use of intraoperative monitoring (IOM) in glioma surgery is a widely adopted and clinically validated adjunct to define safe zones of resection for the neurosurgeon. However, the role of IOM in cases of a significant preexisting motor deficit is questionable.  We describe a case of a 25-year-old with a recurrent presentation of a left paracentral glioblastoma, admitted with intratumoral hemorrhage and subsequent acute severe right-sided weakness. The patient underwent a redo left parietal craniotomy and 5-aminolevulinic acid-guided resection with IOM. The severity of the weakness was not reflected by the pre- and intraoperative cortical motor evoked potentials (MEPs) that were reassuring. The patient's hemiparesis recovered to full power postoperatively.  Preoperative weakness is traditionally accepted as a relative contraindication to IOM and therefore its usefulness is questioned in this context. Our case challenges this assumption. We present the clinical course, review the cranial and spinal literature including the reliability of IOM in cases of preoperative motor deficit, and discuss the need for tailor-made IOM strategies.

Sections du résumé

BACKGROUND BACKGROUND
 The use of intraoperative monitoring (IOM) in glioma surgery is a widely adopted and clinically validated adjunct to define safe zones of resection for the neurosurgeon. However, the role of IOM in cases of a significant preexisting motor deficit is questionable.
CASE DESCRIPTION METHODS
 We describe a case of a 25-year-old with a recurrent presentation of a left paracentral glioblastoma, admitted with intratumoral hemorrhage and subsequent acute severe right-sided weakness. The patient underwent a redo left parietal craniotomy and 5-aminolevulinic acid-guided resection with IOM. The severity of the weakness was not reflected by the pre- and intraoperative cortical motor evoked potentials (MEPs) that were reassuring. The patient's hemiparesis recovered to full power postoperatively.
CONCLUSIONS CONCLUSIONS
 Preoperative weakness is traditionally accepted as a relative contraindication to IOM and therefore its usefulness is questioned in this context. Our case challenges this assumption. We present the clinical course, review the cranial and spinal literature including the reliability of IOM in cases of preoperative motor deficit, and discuss the need for tailor-made IOM strategies.

Identifiants

pubmed: 32221963
doi: 10.1055/s-0039-1698396
doi:

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

387-391

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

None declared.

Auteurs

Ravindran Visagan (R)

Department of Neurosurgery, King's College Hospital NHS Foundation Trust Denmark Hill, London, United Kingdom.

José Pedro Lavrador (JP)

Department of Neurosurgery, King's College Hospital NHS Foundation Trust Denmark Hill, London, United Kingdom.

Shami Acharya (S)

Department of Neurosurgery, King's College Hospital NHS Foundation Trust Denmark Hill, London, United Kingdom.

Noemia Pereira (N)

Department of Clinical Neurophysiology, Inomed Neurocare, London, UK.

Istvan Bodi (I)

Department of Neurosurgery, King's College Hospital NHS Foundation Trust Denmark Hill, London, United Kingdom.

Keyoumars Ashkan (K)

Department of Neurosurgery, King's College Hospital NHS Foundation Trust Denmark Hill, London, United Kingdom.

Ranjeev Bhangoo (R)

Department of Neurosurgery, King's College Hospital NHS Foundation Trust Denmark Hill, London, United Kingdom.

F Vergani (F)

Department of Neurosurgery, King's College Hospital NHS Foundation Trust Denmark Hill, London, United Kingdom.

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