Epidemiology and maternal prognosis of hypertension disorders of pregnancy in French Guiana.
Adult
Cesarean Section
Female
French Guiana
/ epidemiology
HELLP Syndrome
/ epidemiology
Hospitalization
Humans
Hypertension, Pregnancy-Induced
/ diagnosis
Maternal Health
Maternal Mortality
Pre-Eclampsia
/ epidemiology
Pregnancy
Prevalence
Prognosis
Proteinuria
/ epidemiology
Risk Factors
Severity of Illness Index
Young Adult
Eclampsia
Hypertension During Pregnancy
Preeclampsia
Proteinuria
Journal
Pregnancy hypertension
ISSN: 2210-7797
Titre abrégé: Pregnancy Hypertens
Pays: Netherlands
ID NLM: 101552483
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
25
09
2019
revised:
18
02
2020
accepted:
20
03
2020
pubmed:
1
4
2020
medline:
25
8
2020
entrez:
1
4
2020
Statut:
ppublish
Résumé
Hypertensive disorders of pregnancy (HDP) are responsible for high maternal mortality and morbidity worldwide. Our primary objective was to report the epidemiological and clinical features of HDP in Cayenne General Hospital. Our secondary objectives were to search for factors associated to preeclampsia (PE) and to severe PE in patients with HDP. Our study was observational and non-interventional. It was conducted over 4-month period (January to April 2019) in the Obstetrics and Gynaecology Unit of the Cayenne General Hospital. We included all pregnant women after 20 weeks of gestation (WG), who gave birth and who presented HDP and/or PE. During the study period 1243 patients gave birth in our unit. Among them, 156 were diagnosed with HDP (12.6%). The median age was 33 years (IQR 28 - 38 years). The most frequent medical histories were diabetes (27.5%) and chronic hypertension (23.5%). The socioeconomic status was low in 31% of patients. Ninety-four patients (61.4%) developed PE with a severe form in 80.9% of cases. HELLP syndrome was diagnosed in 6.5% and nephropathy in 3.3% of cases. Delivery was by cesarean in 49.7% of cases. The median gestational age at delivery was 37 WG (IQR: 35-39). Multivariate analysis showed no independent factors associated with the occurrence of PE or severe PE in patients with HDP. Our study shows a high prevalence of PE in patients with HDP. Hospitalization and repeated clinical evaluation are needed to screen for women exposed to develop PE or severe PE.
Sections du résumé
BACKGROUND
BACKGROUND
Hypertensive disorders of pregnancy (HDP) are responsible for high maternal mortality and morbidity worldwide.
OBJECTIVE
OBJECTIVE
Our primary objective was to report the epidemiological and clinical features of HDP in Cayenne General Hospital. Our secondary objectives were to search for factors associated to preeclampsia (PE) and to severe PE in patients with HDP.
METHODS
METHODS
Our study was observational and non-interventional. It was conducted over 4-month period (January to April 2019) in the Obstetrics and Gynaecology Unit of the Cayenne General Hospital. We included all pregnant women after 20 weeks of gestation (WG), who gave birth and who presented HDP and/or PE.
RESULTS
RESULTS
During the study period 1243 patients gave birth in our unit. Among them, 156 were diagnosed with HDP (12.6%). The median age was 33 years (IQR 28 - 38 years). The most frequent medical histories were diabetes (27.5%) and chronic hypertension (23.5%). The socioeconomic status was low in 31% of patients. Ninety-four patients (61.4%) developed PE with a severe form in 80.9% of cases. HELLP syndrome was diagnosed in 6.5% and nephropathy in 3.3% of cases. Delivery was by cesarean in 49.7% of cases. The median gestational age at delivery was 37 WG (IQR: 35-39). Multivariate analysis showed no independent factors associated with the occurrence of PE or severe PE in patients with HDP.
CONCLUSION
CONCLUSIONS
Our study shows a high prevalence of PE in patients with HDP. Hospitalization and repeated clinical evaluation are needed to screen for women exposed to develop PE or severe PE.
Identifiants
pubmed: 32224440
pii: S2210-7789(20)30037-4
doi: 10.1016/j.preghy.2020.03.010
pii:
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
96-101Informations de copyright
Copyright © 2020 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.