Grape Stem Extracts From Three Native Greek Vine Varieties Exhibit Strong Antioxidant and Antimutagenic Properties.


Journal

Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988

Informations de publication

Date de publication:
Apr 2020
Historique:
received: 25 02 2020
revised: 10 03 2020
accepted: 11 03 2020
entrez: 3 4 2020
pubmed: 3 4 2020
medline: 11 4 2020
Statut: ppublish

Résumé

The winemaking procedure results in the generation of stems, a by-product that is harmful to the environment. Concomitantly, stems are rich in polyphenols and, hence, they are putatively beneficial for human health. In this study, the grape stem extracts derived from three native Greek vine varieties, namely Mavrodaphne, Muscat and Rhoditis were examined for their chemical composition and antioxidant and antimutagenic properties using a battery of in vitro biomarkers. All extracts are rich in polyphenols. Moreover, they exhibit potent antioxidant and antimutagenic properties with the extract of Mavrodaphne being the strongest in reducing the DPPH Therefore, although they are serious pollutants, grape stems contain phytochemicals with important biological properties and can be used as (ingredients of) bio-functional foods to improve certain aspects of human health.

Sections du résumé

BACKGROUND/AIM OBJECTIVE
The winemaking procedure results in the generation of stems, a by-product that is harmful to the environment. Concomitantly, stems are rich in polyphenols and, hence, they are putatively beneficial for human health.
MATERIALS AND METHODS METHODS
In this study, the grape stem extracts derived from three native Greek vine varieties, namely Mavrodaphne, Muscat and Rhoditis were examined for their chemical composition and antioxidant and antimutagenic properties using a battery of in vitro biomarkers.
RESULTS RESULTS
All extracts are rich in polyphenols. Moreover, they exhibit potent antioxidant and antimutagenic properties with the extract of Mavrodaphne being the strongest in reducing the DPPH
CONCLUSION CONCLUSIONS
Therefore, although they are serious pollutants, grape stems contain phytochemicals with important biological properties and can be used as (ingredients of) bio-functional foods to improve certain aspects of human health.

Identifiants

pubmed: 32234893
pii: 40/4/2025
doi: 10.21873/anticanres.14159
doi:

Substances chimiques

Antioxidants 0
Plant Extracts 0
Polyphenols 0
Reactive Oxygen Species 0
DNA 9007-49-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2025-2032

Informations de copyright

Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Auteurs

Aristidis S Veskoukis (AS)

Department of Biochemistry and Biotechnology, University of Thessaly, Larissa, Greece.

Eleni Vassi (E)

Department of Biochemistry and Biotechnology, University of Thessaly, Larissa, Greece.

Konstantinos Poulas (K)

Department of Pharmacy, University of Patras, Patras, Greece.

Manolis Kokkinakis (M)

Laboratory of Toxicology, School of Medicine, University of Crete, Heraklion, Greece.

Eftihia Asprodini (E)

Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

Serkos Haroutounian (S)

Laboratory of Nutritional Physiology and Feeding, Department of Animal Bioscience, Agricultural University of Athens, Athens, Greece.

Demetrios Kouretas (D)

Department of Biochemistry and Biotechnology, University of Thessaly, Larissa, Greece dkouret@uth.gr.

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Classifications MeSH