Exocrine Pancreatic Insufficiency in Type 1 and Type 2 Diabetes.


Journal

Current diabetes reports
ISSN: 1539-0829
Titre abrégé: Curr Diab Rep
Pays: United States
ID NLM: 101093791

Informations de publication

Date de publication:
01 04 2020
Historique:
entrez: 3 4 2020
pubmed: 3 4 2020
medline: 15 9 2020
Statut: epublish

Résumé

Type 1 and type 2 diabetes are often accompanied by mostly mild forms of exocrine pancreatic insufficiency. Despite high prevalence, little is known about the clinical consequences of exocrine pancreatic insufficiency and its optimal (nutritional) treatment. Even less is known if and to what extent exocrine pancreas insufficiency also affects glycemic control in diabetes. This article aims for summarizing current clinical knowledge on screening, diagnosis, and treatment and gives an overview on the pathophysiology of exocrine pancreatic insufficiency in diabetes. Recent studies reveal novel insights into the close interaction of acinar, ductal, and endocrine cells and the gut-pancreas axis. Exocrine pancreatic insufficiency is a clinically relevant, frequent but poorly understood disorder in both type 1 and type 2 diabetes.

Identifiants

pubmed: 32239341
doi: 10.1007/s11892-020-01304-0
pii: 10.1007/s11892-020-01304-0
pmc: PMC7113197
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

18

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Auteurs

Bernhard Radlinger (B)

Department of Internal Medicine 1, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.

Gabriele Ramoser (G)

Department of Pediatrics II, Medical University Innsbruck, Innsbruck, Austria.

Susanne Kaser (S)

Department of Internal Medicine 1, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. susanne.kaser@i-med.ac.at.

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