questionsmedicales.fr
Maladies de l'appareil digestif
Maladies du pancréas
Insuffisance pancréatique exocrine
Insuffisance pancréatique exocrine : Questions médicales fréquentes
Diagnostic
5
Insuffisance pancréatique exocrine
Tests de fonction pancréatique
Échographie
Imagerie par résonance magnétique
Diarrhée
Douleur abdominale
Test de stimulation
Enzymes pancréatiques
Symptômes
5
Malnutrition
Carences vitaminiques
Douleur abdominale
Digestion
Symptômes
Variabilité interindividuelle
Prévention
5
Prévention
Mode de vie sain
Fibrose kystique
Maladies héréditaires
Diabète
Problèmes pancréatiques
Suivi médical
Détection précoce
Traitements
5
Supplémentation enzymatique
Enzymes pancréatiques
Régime alimentaire
Protéines
Médicaments
Symptômes digestifs
Gestion des symptômes
Traitement
Complications
5
Malnutrition
Carences vitaminiques
Infections gastro-intestinales
Malabsorption
Troubles digestifs
Insuffisance pancréatique
Cancer du pancréas
Risque accru
Facteurs de risque
5
Alcoolisme
Maladies héréditaires
Antécédents familiaux
Maladies pancréatiques
Tabagisme
Maladies pancréatiques
Maladies auto-immunes
Pancréas
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"name": "Comment diagnostiquer l'insuffisance pancréatique exocrine ?",
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"text": "Le diagnostic se fait par des tests de fonction pancréatique, comme le dosage de l'élastase fécale."
}
},
{
"@type": "Question",
"name": "Quels tests sanguins sont utilisés pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins mesurant les niveaux de lipase et d'amylase peuvent être effectués."
}
},
{
"@type": "Question",
"name": "Les examens d'imagerie sont-ils nécessaires ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des échographies ou IRM peuvent aider à visualiser des anomalies pancréatiques."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent un besoin de diagnostic ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme la diarrhée grasse, la perte de poids et des douleurs abdominales peuvent indiquer un problème."
}
},
{
"@type": "Question",
"name": "Le test de stimulation du pancréas est-il courant ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il évalue la capacité du pancréas à produire des enzymes après stimulation."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes principaux de cette condition ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent diarrhée, perte de poids, ballonnements et douleurs abdominales."
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{
"@type": "Question",
"name": "La diarrhée est-elle toujours grasse ?",
"position": 7,
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"@type": "Question",
"name": "Y a-t-il des symptômes liés à la malnutrition ?",
"position": 8,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Les douleurs abdominales sont-elles fréquentes ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des douleurs abdominales peuvent survenir, souvent liées à la digestion."
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{
"@type": "Question",
"name": "Les symptômes varient-ils d'une personne à l'autre ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'intensité et la combinaison des symptômes peuvent varier selon les individus."
}
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{
"@type": "Question",
"name": "Peut-on prévenir l'insuffisance pancréatique exocrine ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un mode de vie sain peut réduire les risques."
}
},
{
"@type": "Question",
"name": "Les maladies héréditaires augmentent-elles le risque ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies génétiques comme la fibrose kystique augmentent le risque."
}
},
{
"@type": "Question",
"name": "L'alcoolisme est-il un facteur de risque ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'alcoolisme chronique peut endommager le pancréas et entraîner une insuffisance."
}
},
{
"@type": "Question",
"name": "Le diabète influence-t-il le risque ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le diabète peut être associé à des problèmes pancréatiques, augmentant le risque."
}
},
{
"@type": "Question",
"name": "Un suivi médical régulier est-il conseillé ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi régulier peut aider à détecter précocement des problèmes pancréatiques."
}
},
{
"@type": "Question",
"name": "Quel est le traitement principal de l'insuffisance pancréatique ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement principal consiste en la supplémentation en enzymes pancréatiques."
}
},
{
"@type": "Question",
"name": "Les changements alimentaires sont-ils nécessaires ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un régime riche en protéines et faible en graisses est souvent recommandé."
}
},
{
"@type": "Question",
"name": "Des médicaments sont-ils prescrits ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments pour soulager les symptômes digestifs peuvent être prescrits."
}
},
{
"@type": "Question",
"name": "La surveillance médicale est-elle importante ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi régulier est essentiel pour ajuster le traitement et surveiller la nutrition."
}
},
{
"@type": "Question",
"name": "Peut-on guérir l'insuffisance pancréatique ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'y a pas de cure, mais les symptômes peuvent être gérés efficacement avec un traitement."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent la malnutrition, les carences vitaminiques et des troubles digestifs."
}
},
{
"@type": "Question",
"name": "L'insuffisance pancréatique peut-elle entraîner le diabète ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une insuffisance pancréatique peut affecter la production d'insuline, menant au diabète."
}
},
{
"@type": "Question",
"name": "Des infections peuvent-elles survenir ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des infections gastro-intestinales peuvent survenir en raison de la malabsorption."
}
},
{
"@type": "Question",
"name": "Les troubles de la digestion sont-ils fréquents ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles digestifs chroniques peuvent résulter de l'insuffisance pancréatique."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque accru de cancer ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines études suggèrent un risque accru de cancer du pancréas chez ces patients."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les principaux facteurs incluent l'alcoolisme, les maladies héréditaires et le diabète."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque d'insuffisance pancréatique augmente avec l'âge."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies pancréatiques augmentent le risque."
}
},
{
"@type": "Question",
"name": "Le tabagisme est-il un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme est associé à un risque accru de maladies pancréatiques."
}
},
{
"@type": "Question",
"name": "Les maladies auto-immunes augmentent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies auto-immunes peuvent affecter le pancréas et augmenter le risque."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 07/02/2026
Contenu vérifié selon les dernières recommandations médicales
5 publications dans cette catégorie
Affiliations :
Department of HPB and Liver Transplantation, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham B15 2TH, United Kingdom.
Publications dans "Insuffisance pancréatique exocrine" :
4 publications dans cette catégorie
Affiliations :
Department for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden - miroslav.vujasinovic@sll.se.
Publications dans "Insuffisance pancréatique exocrine" :
3 publications dans cette catégorie
Affiliations :
Department of Gastroenterology, S. Andrea Hospital, Rome.
Publications dans "Insuffisance pancréatique exocrine" :
3 publications dans cette catégorie
Affiliations :
2Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, IL.
Publications dans "Insuffisance pancréatique exocrine" :
3 publications dans cette catégorie
Affiliations :
2Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, IL.
Publications dans "Insuffisance pancréatique exocrine" :
3 publications dans cette catégorie
Affiliations :
Department for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden.
Department of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden.
Publications dans "Insuffisance pancréatique exocrine" :
3 publications dans cette catégorie
Affiliations :
Division of Digestive Health and Liver Diseases, Department of Medicine, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida.
Publications dans "Insuffisance pancréatique exocrine" :
3 publications dans cette catégorie
Affiliations :
Department of Internal Medicine 1, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. susanne.kaser@i-med.ac.at.
Publications dans "Insuffisance pancréatique exocrine" :
3 publications dans cette catégorie
Affiliations :
Department of HPB and Liver Transplantation, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham B15 2TH, United Kingdom.
Publications dans "Insuffisance pancréatique exocrine" :
3 publications dans cette catégorie
Affiliations :
Liver Unit, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham, Birmingham, UK.
College of Medical and Dental Scientists, University of Birmingham, Birmingham, UK.
Publications dans "Insuffisance pancréatique exocrine" :
2 publications dans cette catégorie
Affiliations :
Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Publications dans "Insuffisance pancréatique exocrine" :
2 publications dans cette catégorie
Affiliations :
Division of Pediatric Gastroenterology, Department of Pediatrics, UH Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Publications dans "Insuffisance pancréatique exocrine" :
2 publications dans cette catégorie
Affiliations :
Division of Pediatric Pulmonology, Department of Pediatrics, UH Rainbow Babies & Children's Hospital, Cleveland, Ohio, USA.
Publications dans "Insuffisance pancréatique exocrine" :
2 publications dans cette catégorie
Affiliations :
Department of Gastroenterology, San Cecilio University Hospital, 18012 Granada, Spain.
Publications dans "Insuffisance pancréatique exocrine" :
2 publications dans cette catégorie
Affiliations :
Institute of Biopathology and Regenerative Medicine (IBIMER), University of Granada, 18100 Granada, Spain.
Publications dans "Insuffisance pancréatique exocrine" :
2 publications dans cette catégorie
Affiliations :
Institute of Biopathology and Regenerative Medicine (IBIMER), University of Granada, 18100 Granada, Spain.
Publications dans "Insuffisance pancréatique exocrine" :
2 publications dans cette catégorie
Affiliations :
Department of General Surgery, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.
Acute Pancreatitis Clinical Center of Capital Medical University, Beijing 100053, China.
Publications dans "Insuffisance pancréatique exocrine" :
2 publications dans cette catégorie
Affiliations :
Department of General Surgery, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.
Acute Pancreatitis Clinical Center of Capital Medical University, Beijing 100053, China.
Publications dans "Insuffisance pancréatique exocrine" :
2 publications dans cette catégorie
Affiliations :
Department of General Surgery, Xuanwu Hospital of Capital Medical University, Beijing 100053, China. feili36@ccmu.edu.cn.
Acute Pancreatitis Clinical Center of Capital Medical University, Beijing 100053, China. feili36@ccmu.edu.cn.
Publications dans "Insuffisance pancréatique exocrine" :
2 publications dans cette catégorie
Affiliations :
Department of Hepatobiliary Transplantation and Endocrine Surgery, Antwerp University Hospital and University of Antwerp, Edegem. Electronic address: Geert.Roeyen@uza.be.
Publications dans "Insuffisance pancréatique exocrine" :
This study explores the optimization of exocrine pancreatic insufficiency (EPI) management in pancreatic adenocarcinoma patients, focusing on the scientific advancements and technological intervention...
Patients were contacted at pre-defined intervals (prior to surgery, before hospital discharge, and 2, 4, 6, and 12 weeks after surgery) to complete nutrition evaluation, EPI assessment, and quality of...
EPI symptoms were reported in 28 of the 35 total patients studied (80%). Jejunostomy tubes were placed during oncologic surgery in 25 of the 35 total patients studied (71%), and 12 of the 25 patients ...
Overall, early optimization of EPI is crucial to enhance overall patient care, return to oncology therapy after surgery, and improve quality of life in pancreatic adenocarcinoma patients....
/Objective: The extent of exocrine pancreatic insufficiency (EPI) in the paediatric population with acute pancreatitis (AP) is unknown. The primary objective was to use a 6 h stable-isotope breath tes...
The cPDR of cases was significantly lower than that of controls (27.71 ± 7.88% vs 36.37 ± 4.70%, p = 0.005). The cPDR during acute illness was not significantly different to that at 1 month follow up ...
Two-thirds (66.7%) of this sample of children with AP had EPI during admission, which persisted at 1 month follow up. The 4 h abbreviated...
Patients undergoing pancreatic surgery are at risk of pancreatic exocrine insufficiency (PEI) and needing pancreatic enzyme replacement therapy (PERT)....
This study included 254 patients undergoing pancreatic surgery for oncologic indications. A...
In 197 patients undergoing pancreaticoduodenectomy, cPDR-6h decreased significantly from a median of 32.84% before to 15.80% after surgery (p < 0.0001). This decrease in exocrine function was signific...
The vast majority of patients undergoing pancreaticoduodenectomy for oncologic indications experience a significant drop in exocrine function, are at high risk of developing pancreatic exocrine insuff...
The diagnosis and management of exocrine pancreatic dysfunction (EPD) can be challenging. EPD classically results from conditions that cause loss of pancreatic acinar cell function and decreased diges...
An EPD severity classification schema has been proposed, which emphasizes a shift towards a more restrictive prescription of pancreas enzyme replacement therapy (PERT) for patients with milder EPD. In...
Among individuals with severe EPD, PERT is an effective therapy. Among individuals with milder EPD, although PERT is effective, there may be opportunities to provide additional and potentially more ef...
Apolipoprotein A2 (apoA2) isoforms have been reported to undergo the aberrant processing in pancreatic cancer and pancreatic risk populations compared with that in healthy subjects. This study aimed t...
Fifty consecutive patients with functional dyspepsia with pancreatic enzyme abnormalities (FD-P) (n = 18), with ECP (n = 20), and asymptomatic patients with pancreatic enzyme abnormalities (AP-P) (n =...
There were no significant differences in clinical characteristics such as age, gender, body mass index, alcohol consumption and smoking among patients with AP-P, FD-P, and ECP. The BT-PABA test and li...
ApoA2-AT level is a useful tool to evaluate exocrine pancreatic insufficiency in the early stage of chronic pancreatitis....
Most patients with chronic pancreatitis (CP) develop pancreatic exocrine insufficiency (PEI) over the course of the disease. PEI may lead to hyperoxaluria and development of urinary oxalate stones. It...
We performed retrospective analysis of an electronical medical database of patients diagnosed with definite CP during 2003-2020. We excluded patients <18 years of age, those with missing relevant data...
Some 632 patients with definite CP were followed over a median of 5.3 (IQR 2.4-6.9) years. There were 41 (6.5%) patients diagnosed with kidney stones, of whom 33 (80.5%) were symptomatic. Comparing to...
PEI and increase in BMI are risk factors for kidney stone development in patients with CP. Male CP patents are particularly at increased risk of nephrolithiasis. This should be taken into consideratio...
The heterogenous category "specific types of diabetes due to other causes" encompasses disturbances in glucose metabolism due to other endocrine disorders such as acromegaly or hypercortisolism, drug-...
Exocrine pancreatic insufficiency (EPI) is a critical host factor in determining the composition of the gut microbiota. Diseases that cause exocrine insufficiency can affect the gut microbiome, which ...
To conduct a comparative analysis of the taxonomic composition of the intestinal microbiota in patients with CP of various etiologies, without or with the presence of EPI of varying severity, as well ...
A total of 85 patients were included in the study. Patients were divided into groups according to the severity of EPI: Group 1 (...
We followed the changes in the gut microbiota from a group of patients with CP without EPI to a group with severe EPI, in those who underwent SI. At the level of the phylum, the IM of all groups showe...
The results of the study show that patients with CP of various etiologies and patients with severe EPI who underwent specific intervention on the pancreas have intestinal microbiota dysbiosis, the sev...
The prevalence of celiac disease (CD) is approximately 1% in the US. Studies have shown possible association between exocrine pancreatic insufficiency (EPI) and CD, with numerous hypothesized biologic...
Pediatric patients with exocrine pancreatic insufficiency (EPI) have symptoms that include abdominal pain, weight loss or poor weight gain, malnutrition, and steatorrhea. This condition can be present...