Longitudinal cohort of HIV-negative transgender women of colour in New York City: protocol for the TURNNT ('Trying to Understand Relationships, Networks and Neighbourhoods among Transgender women of colour') study.
Adolescent
Adult
Black or African American
/ statistics & numerical data
Asian
/ statistics & numerical data
Asian People
/ statistics & numerical data
Cross-Sectional Studies
Female
HIV Infections
/ prevention & control
HIV Seronegativity
Hispanic or Latino
/ statistics & numerical data
Humans
Interpersonal Relations
Male
Middle Aged
Multivariate Analysis
Native Hawaiian or Other Pacific Islander
/ statistics & numerical data
New York City
/ ethnology
Prospective Studies
Residence Characteristics
Sexual Partners
Social Networking
Transgender Persons
/ statistics & numerical data
Young Adult
HIV & AIDS
epidemiology
sexual medicine
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
01 04 2020
01 04 2020
Historique:
entrez:
4
4
2020
pubmed:
4
4
2020
medline:
13
2
2021
Statut:
epublish
Résumé
In the USA, transgender women are among the most vulnerable to HIV. In particular, transgender women of colour face high rates of infection and low uptake of important HIV prevention tools, including pre-exposure prophylaxis (PrEP). This paper describes the design, sampling methods, data collection and analyses of the TURNNT ('Trying to Understand Relationships, Networks and Neighbourhoods among Transgender women of colour') study. In collaboration with communities of transgender women of colour, TURNNT aims to explore the complex social and environmental (ie, neighbourhood) structures that affect HIV prevention and other aspects of health in order to identify avenues for intervention. TURNNT is a prospective cohort study, which will recruit 300 transgender women of colour (150 Black/African American, 100 Latina and 50 Asian/Pacific Islander participants) in New York City. There will be three waves of data collection separated by 6 months. At each wave, participants will provide information on their relationships, social and sexual networks, and neighbourhoods. Global position system technology will be used to generate individual daily path areas in order to estimate neighbourhood-level exposures. Multivariate analyses will be conducted to assess cross-sectional and longitudinal, independent and synergistic associations of personal relationships (notably individual social capital), social and sexual networks, and neighbourhood factors (notably neighbourhood-level social cohesion) with PrEP uptake and discontinuation. The TURNNT protocol was approved by the Columbia University Institutional Review Board (reference no. AAAS8164). This study will provide novel insights into the relationship, network and neighbourhood factors that influence HIV prevention behaviours among transgender women of colour and facilitate exploration of this population's health and well-being more broadly. Through community-based dissemination events and consultation with policy makers, this foundational work will be used to guide the development and implementation of future interventions with and for transgender women of colour.
Identifiants
pubmed: 32241785
pii: bmjopen-2019-032876
doi: 10.1136/bmjopen-2019-032876
pmc: PMC7170618
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e032876Subventions
Organisme : NIMH NIH HHS
ID : P30 MH062246
Pays : United States
Organisme : NIMHD NIH HHS
ID : R01 MD013554
Pays : United States
Organisme : NIMH NIH HHS
ID : R25 MH083620
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Informations de copyright
© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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