Reduced symptom burden with the support of an interactive app during neoadjuvant chemotherapy for breast cancer - A randomized controlled trial.
Breast cancer
HRQoL
Neoadjuvant chemotherapy
RCT
Symptom burden
mHealth
Journal
Breast (Edinburgh, Scotland)
ISSN: 1532-3080
Titre abrégé: Breast
Pays: Netherlands
ID NLM: 9213011
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
09
12
2019
revised:
12
02
2020
accepted:
19
03
2020
pubmed:
5
4
2020
medline:
24
2
2021
entrez:
5
4
2020
Statut:
ppublish
Résumé
Neoadjuvant chemotherapy causes distressing symptoms, which have to be managed by patients at home. Assessing and acting upon relevant patient-reported symptoms regularly with the support of mHealth such as apps, has shown to decrease symptom burden and improve health-related quality of life (HRQoL). There is a lack of apps for patients with breast cancer which are tested in rigorous trials and only a few include interactive components for immediate clinical management. The aim of this study was to evaluate whether the use of the interactive app Interaktor improves patients' levels of symptom burden and HRQoL during neoadjuvant chemotherapy for breast cancer. This randomized controlled trial included patients in an intervention group (n = 74) and a control group (n = 75), recruited at two university hospitals in Stockholm, Sweden. The intervention group used Interaktor for symptom reporting, self-care advice and support from health-care professionals during treatment, and the control group received standard care alone. Self-reported symptoms and HRQoL were assessed at two time points to determine differences between the groups. The intervention group rated statistically significant less symptom prevalence in nausea, vomiting, feeling sad, appetite loss and constipation. Overall symptom distress and physical symptom distress were rated statistically significant lower in the intervention group. Further, emotional functioning was rated statistically significant higher in the intervention group. By using the Interaktor app in clinical practice, patients get individual support when managing treatment-related symptoms during neoadjuvant chemotherapy for breast cancer, leading to decreased symptom burden and improved emotional functioning.
Identifiants
pubmed: 32247251
pii: S0960-9776(20)30083-7
doi: 10.1016/j.breast.2020.03.004
pmc: PMC7375618
pii:
doi:
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
85-93Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors of this manuscript declare no conflict of interests.
Références
JMIR Mhealth Uhealth. 2017 Dec 04;5(12):e187
pubmed: 29203459
Support Care Cancer. 2017 Feb;25(2):409-419
pubmed: 27696078
Eur J Cancer. 2018 Sep;101:1-11
pubmed: 30014970
Int J Med Inform. 2018 Feb;110:1-9
pubmed: 29331247
J Occup Rehabil. 2007 Mar;17(1):83-92
pubmed: 17318459
Eur J Oncol Nurs. 2016 Feb;20:77-86
pubmed: 26078034
J Biomed Inform. 2020 Jan;101:103342
pubmed: 31816400
Health Qual Life Outcomes. 2018 Jun 4;16(1):114
pubmed: 29866185
Intern Med J. 2018 May;48(5):583-587
pubmed: 29722200
Support Care Cancer. 2017 Jul;25(7):2195-2204
pubmed: 28236145
J Med Internet Res. 2013 May 21;15(5):e95
pubmed: 23697600
J Clin Oncol. 1998 Jan;16(1):139-44
pubmed: 9440735
Ann Surg Oncol. 2015 May;22(5):1408-15
pubmed: 25727557
Ann Surg Oncol. 2015 Oct;22(10):3376-82
pubmed: 26202561
JMIR Cancer. 2017 Oct 31;3(2):e18
pubmed: 29089290
Support Care Cancer. 2011 Jul;19(7):963-9
pubmed: 20499108
Eur J Oncol Nurs. 2013 Feb;17(1):22-9
pubmed: 22449715
Breast. 2016 Aug;28:20-8
pubmed: 27173849
Patient Prefer Adherence. 2010 Feb 04;4:11-6
pubmed: 20165594
Online J Public Health Inform. 2014 Feb 05;5(3):229
pubmed: 24683442
Eur J Cancer. 1994;30A(9):1326-36
pubmed: 7999421
Eur J Oncol Nurs. 2017 Jun;28:122-132
pubmed: 28478849
Lancet Oncol. 2018 Jan;19(1):27-39
pubmed: 29242041
J Natl Cancer Inst. 1993 Mar 3;85(5):365-76
pubmed: 8433390
J Pain Symptom Manage. 2013 Jul;46(1):131-41
pubmed: 23195392
J Natl Cancer Inst. 2017 Sep 1;109(9):
pubmed: 28423407
J Clin Oncol. 2016 Feb 20;34(6):557-65
pubmed: 26644527
Support Care Cancer. 2018 Feb;26(2):337-351
pubmed: 28921391
J Chronic Dis. 1987;40(5):373-83
pubmed: 3558716
Cancer. 2014 Aug 1;120(15):2371-8
pubmed: 24797450
Breast. 2013 Oct;22(5):593-605
pubmed: 24001709
Clin Oncol (R Coll Radiol). 2017 Oct;29(10):642-652
pubmed: 28669449
Gland Surg. 2017 Feb;6(1):119-124
pubmed: 28210563
Breast Cancer Res Treat. 2019 Dec;178(3):703-711
pubmed: 31512091
Cancer Nurs. 2019 May/Jun;42(3):E1-E10
pubmed: 29596113
J Clin Pathol. 2019 Feb;72(2):120-132
pubmed: 30670564
Biometrics. 2017 Dec;73(4):1366-1378
pubmed: 28199733
JAMA. 2019 Jan 22;321(3):306-307
pubmed: 30667494
Eur J Cancer. 2012 Jul;48(11):1713-21
pubmed: 22418017
BMC Cancer. 2017 Jul 4;17(1):466
pubmed: 28676102
Cancer Nurs. 2013 Jan-Feb;36(1):6-17
pubmed: 22495503
Eur J Cancer Care (Engl). 2011 Jul;20(4):424-35
pubmed: 20825463
J Adv Nurs. 2017 Oct;73(10):2339-2350
pubmed: 28370172
Int J Older People Nurs. 2018 Jun;13(2):e12181
pubmed: 29210218
J Clin Nurs. 2017 Jun;26(11-12):1575-1583
pubmed: 27381423
Support Care Cancer. 2017 Apr;25(4):1323-1355
pubmed: 28058570
Support Care Cancer. 2017 May;25(5):1423-1429
pubmed: 27981366
Eur J Oncol Nurs. 2018 Aug;35:85-91
pubmed: 30057089