A comparison of the satiating properties of medium-chain triglycerides and conjugated linoleic acid in participants with healthy weight and overweight or obesity.
Appetite
Energy intake
Food intake
Gut-peptide hormones
Ketones
Lipids
Journal
European journal of nutrition
ISSN: 1436-6215
Titre abrégé: Eur J Nutr
Pays: Germany
ID NLM: 100888704
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
24
07
2019
accepted:
25
03
2020
pubmed:
6
4
2020
medline:
24
6
2021
entrez:
6
4
2020
Statut:
ppublish
Résumé
Inconsistent evidence exists for greater satiety after medium-chain triglycerides (MCT) or conjugated linoleic acid (CLA) compared to long-chain triglycerides (LCT). Furthermore, the mechanisms are poorly understood and effects in people with a healthy weight and those with overweight/obesity have not been compared. This study aimed to compare appetite responses in these groups and examine the mechanisms behind any differences. Fifteen participants with healthy weight (BMI: 22.7 ± 1.9 kg·m Neither MCT nor CLA decreased ad libitum intake; however MCT decreased day 1 energy intake (P = 0.031) and the 48-h period (P = 0.005) compared to CON. MCT delayed GE (P ≤ 0.01) compared to CON, whereas CLA did not. PYY and TG concentrations were not different (P = 0.743 and P = 0.188, respectively), but MCT increased β-hydroxybutyrate concentrations compared to CON (P = 0.005) and CLA (P < 0.001). β-hydroxybutyrate concentrations were higher in participants with overweight/obesity (P = 0.009). Consumption of MCT reduces energy intake in the subsequent 48 h, whereas CLA does not. Delayed gastric emptying or increased β-hydroxybutyrate concentrations may mediate this.
Identifiants
pubmed: 32248292
doi: 10.1007/s00394-020-02235-y
pii: 10.1007/s00394-020-02235-y
pmc: PMC7867511
doi:
Substances chimiques
Linoleic Acids, Conjugated
0
Triglycerides
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
203-215Subventions
Organisme : x
ID : Tanita Healthy Weight Community Trust
Références
Br J Nutr. 1998 May;79(5):425-9
pubmed: 9682661
J Clin Endocrinol Metab. 2008 May;93(5):1971-9
pubmed: 18198223
J Nutr. 2005 Apr;135(4):778-84
pubmed: 15795434
Appetite. 2010 Jun;54(3):450-5
pubmed: 20416348
Neurosci Lett. 2007 May 18;418(3):217-21
pubmed: 17466453
Am J Physiol Regul Integr Comp Physiol. 2004 Sep;287(3):R524-33
pubmed: 15166004
Obes Rev. 2010 Mar;11(3):251-70
pubmed: 20122136
Appetite. 1989 Dec;13(3):183-91
pubmed: 2596841
Obesity (Silver Spring). 2018 Feb;26(2):269-273
pubmed: 29105987
Aliment Pharmacol Ther. 2011 Apr;33(8):880-94
pubmed: 21342212
Physiol Behav. 2010 Aug 4;101(1):161-7
pubmed: 20451538
Int J Sports Med. 1992 Nov;13(8):581-4
pubmed: 1487341
Diabetes. 2009 May;58(5):1237-44
pubmed: 19223595
Dig Dis Sci. 1998 May;43(5):945-52
pubmed: 9590405
J Psychosom Res. 1985;29(1):71-83
pubmed: 3981480
Acta Endocrinol (Copenh). 1970 Sep;65(1):155-69
pubmed: 5468968
J Oleo Sci. 2007;56(6):283-7
pubmed: 17898493
J Clin Invest. 1986 Mar;77(3):992-6
pubmed: 3949984
Eur J Nutr. 2013 Sep;52(6):1579-85
pubmed: 23179202
Gastroenterology. 1985 Nov;89(5):1070-7
pubmed: 3840109
Gastroenterology. 1999 Jan;116(1):46-53
pubmed: 9869601
Int J Obes (Lond). 2006 Oct;30(10):1476-81
pubmed: 16702998
Br J Nutr. 2007 Mar;97(3):550-60
pubmed: 17313718
Physiol Behav. 2016 Oct 1;164(Pt A):40-6
pubmed: 27235735
J Physiol. 1998 Nov 15;513 ( Pt 1):11-8
pubmed: 9782155
J Endocrinol. 2005 Feb;184(2):291-318
pubmed: 15684339
J Pediatr. 1978 Jul;93(1):62-6
pubmed: 650346
J Nutr. 2000 Dec;130(12):2943-8
pubmed: 11110851
Am J Clin Nutr. 2000 Jun;71(6 Suppl):1660S-4S; discussion 1674S-5S
pubmed: 10837311
Am J Clin Nutr. 2004 Jun;79(6):946-61
pubmed: 15159223
Isotopes Environ Health Stud. 1997 Jul;33(1-2):135-43
pubmed: 22087491
Physiol Behav. 2017 Oct 1;179:422-426
pubmed: 28689741
JPEN J Parenter Enteral Nutr. 1999 Jul-Aug;23(4):203-6
pubmed: 10421388
Obes Res. 2001 Feb;9(2):129-34
pubmed: 11316347
J Nutr. 2003 Oct;133(10):3041-6
pubmed: 14519781
Gut. 2006 Jan;55(1):135
pubmed: 16344585
Eur J Clin Nutr. 2014 Oct;68(10):1134-40
pubmed: 25074387
Am J Clin Nutr. 1998 Aug;68(2):226-34
pubmed: 9701177
Am J Clin Nutr. 2001 Nov;74(5):620-30
pubmed: 11684530
J Nutr. 2000 Feb;130(2):208-15
pubmed: 10720171
Am J Clin Nutr. 1988 Jul;48(1):66-71
pubmed: 3389331
Gut. 2000 May;46(5):688-693
pubmed: 10764713
Am J Clin Nutr. 1982 Nov;36(5):950-62
pubmed: 6814231
Am J Clin Nutr. 2000 Sep;72(3):694-701
pubmed: 10966886
Peptides. 2006 Jul;27(7):1638-43
pubmed: 16563563
J Nutr. 2003 Jan;133(1):257S-260S
pubmed: 12514304
Crit Rev Food Sci Nutr. 2019;59(10):1619-1644
pubmed: 29359954
Nutr Res. 2016 Jun;36(6):526-33
pubmed: 27188898
Am J Physiol. 1951 Aug;166(2):451-5
pubmed: 14857202
Int J Obes (Lond). 2016 Apr;40(4):622-32
pubmed: 26499438
Lipids. 1997 Aug;32(8):853-8
pubmed: 9270977
Int J Obes Relat Metab Disord. 2000 Jul;24(7):899-905
pubmed: 10918538
J Physiol. 2007 Jun 1;581(Pt 2):767-77
pubmed: 17331985
N Engl J Med. 2003 Sep 4;349(10):941-8
pubmed: 12954742
Gastroenterology. 1993 Jun;104(6):1640-7
pubmed: 8500721
J Cereb Blood Flow Metab. 2013 Aug;33(8):1307-11
pubmed: 23736643
Eur J Clin Invest. 1998 Feb;28(2):123-30
pubmed: 9541126