A neuroimaging biomarker for striatal dysfunction in schizophrenia.

Adolescent Adult Antipsychotic Agents / therapeutic use Biomarkers / analysis Biomarkers, Pharmacological / analysis Brain Mapping / methods Case-Control Studies Corpus Striatum / diagnostic imaging Female Functional Neuroimaging / methods Humans Magnetic Resonance Imaging / methods Male Middle Aged Neuroimaging / methods Reproducibility of Results Research Design Schizophrenia / diagnosis Sensitivity and Specificity Support Vector Machine Young Adult

Journal

Nature medicine
ISSN: 1546-170X
Titre abrégé: Nat Med
Pays: United States
ID NLM: 9502015

Informations de publication

Date de publication:
04 2020
Historique:
received: 06 10 2018
accepted: 10 02 2020
pubmed: 7 4 2020
medline: 23 7 2020
entrez: 7 4 2020
Statut: ppublish

Résumé

Mounting evidence suggests that function and connectivity of the striatum is disrupted in schizophrenia

Identifiants

DOI: 10.1038/s41591-020-0793-8 PMID: 32251404
pubmed: 32251404
doi: 10.1038/s41591-020-0793-8
pii: 10.1038/s41591-020-0793-8
doi:

Substances chimiques

Antipsychotic Agents 0
Biomarkers 0
Biomarkers, Pharmacological 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Validation Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

558-565

Références

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Auteurs

Ang Li (A)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.
Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.

Andrew Zalesky (A)

Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Melbourne, Victoria, Australia.
Department of Biomedical Engineering, University of Melbourne, Melbourne, Victoria, Australia.

Weihua Yue (W)

Institute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Key Laboratory of Mental Health, Ministry of Health, and National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.
ORCID: 0000-0002-1201-8465

Oliver Howes (O)

Psychiatric Imaging Group, MRC London Institute of Medical Sciences (Imperial College London), Hammersmith Hospital, London, UK.
Institute of Psychiatry, King's College London, London, UK.

Hao Yan (H)

Institute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Key Laboratory of Mental Health, Ministry of Health, and National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.
ORCID: 0000-0003-0376-9037

Yong Liu (Y)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.
Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.
ORCID: 0000-0002-1862-3121

Lingzhong Fan (L)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.
Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.

Kirstie J Whitaker (KJ)

Department of Psychiatry, University of Cambridge, Cambridge, UK.
The Alan Turing Institute, British Library, London, UK.

Kaibin Xu (K)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.

Guangxiang Rao (G)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.
Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.

Jin Li (J)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.

Shu Liu (S)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.
Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.

Meng Wang (M)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.
Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.

Yuqing Sun (Y)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.
Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.

Ming Song (M)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.

Peng Li (P)

Institute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Key Laboratory of Mental Health, Ministry of Health, and National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.

Jun Chen (J)

Department of Radiology, Renmin Hospital of Wuhan University, Wuhan, China.

Yunchun Chen (Y)

Department of Psychiatry, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

Huaning Wang (H)

Department of Psychiatry, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

Wenming Liu (W)

Department of Psychiatry, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

Zhigang Li (Z)

Zhumadian Psychiatric Hospital, Zhumadian, China.

Yongfeng Yang (Y)

Department of Psychiatry, Henan Mental Hospital, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Henan Key Lab of Biological Psychiatry of Xinxiang Medical University, International Joint Research Laboratory for Psychiatry and Neuroscience of Henan, Xinxiang, China.

Hua Guo (H)

Zhumadian Psychiatric Hospital, Zhumadian, China.

Ping Wan (P)

Zhumadian Psychiatric Hospital, Zhumadian, China.

Luxian Lv (L)

Department of Psychiatry, Henan Mental Hospital, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Henan Key Lab of Biological Psychiatry of Xinxiang Medical University, International Joint Research Laboratory for Psychiatry and Neuroscience of Henan, Xinxiang, China.

Lin Lu (L)

Institute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Key Laboratory of Mental Health, Ministry of Health, and National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.

Jun Yan (J)

Institute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Key Laboratory of Mental Health, Ministry of Health, and National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.

Yuqing Song (Y)

Institute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Key Laboratory of Mental Health, Ministry of Health, and National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.

Huiling Wang (H)

Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.

Hongxing Zhang (H)

Department of Psychiatry, Henan Mental Hospital, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Henan Key Lab of Biological Psychiatry of Xinxiang Medical University, International Joint Research Laboratory for Psychiatry and Neuroscience of Henan, Xinxiang, China.
Department of Psychology, Xinxiang Medical University, Xinxiang, China.

Huawang Wu (H)

The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China.

Yuping Ning (Y)

The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China.

Yuhui Du (Y)

School of Computer and Information Technology, Shanxi University, Taiyuan, China.

Yuqi Cheng (Y)

Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, Kunming, China.

Jian Xu (J)

Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, Kunming, China.

Xiufeng Xu (X)

Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, Kunming, China.

Dai Zhang (D)

Institute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Key Laboratory of Mental Health, Ministry of Health, and National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.
Center for Life Sciences/ PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, China.

Xiaoqun Wang (X)

School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.
Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.
State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

Tianzi Jiang (T)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China. jiangtz@nlpr.ia.ac.cn.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China. jiangtz@nlpr.ia.ac.cn.
Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China. jiangtz@nlpr.ia.ac.cn.
Innovation Academy for Artificial Intelligence, Chinese Academy of Sciences, Beijing, China. jiangtz@nlpr.ia.ac.cn.
Key Laboratory for Neuro Information of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China. jiangtz@nlpr.ia.ac.cn.
Queensland Brain Institute, University of Queensland, Brisbane, Australia. jiangtz@nlpr.ia.ac.cn.
ORCID: 0000-0001-9531-291X

Bing Liu (B)

Brainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China. bliu@nlpr.ia.ac.cn.
School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China. bliu@nlpr.ia.ac.cn.
Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China. bliu@nlpr.ia.ac.cn.
Innovation Academy for Artificial Intelligence, Chinese Academy of Sciences, Beijing, China. bliu@nlpr.ia.ac.cn.
ORCID: 0000-0003-2029-5187

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