Crystal structures of lysophospholipid-bound MHC class I molecules.
MHC class I
Mamu-B
adaptive immunity
antigen presentation
human immunodeficiency virus (HIV)
lipopeptide
lysophospholipid
major histocompatibility complex (MHC)
self-peptide
structural biology
transporter associated with antigen processing (TAP)
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
15 05 2020
15 05 2020
Historique:
received:
18
11
2019
revised:
03
04
2020
pubmed:
10
4
2020
medline:
29
12
2020
entrez:
10
4
2020
Statut:
ppublish
Résumé
Newly synthesized major histocompatibility complex (MHC) class I proteins are stabilized in the endoplasmic reticulum (ER) by binding 8-10-mer-long self-peptide antigens that are provided by transporter associated with antigen processing (TAP). These MHC class I:peptide complexes then exit the ER and reach the plasma membrane, serving to sustain the steady-state MHC class I expression on the cell surface. A novel subset of MHC class I molecules that preferentially bind lipid-containing ligands rather than conventional peptides was recently identified. The primate classical MHC class I allomorphs, Mamu-B*098 and Mamu-B*05104, are capable of binding the
Identifiants
pubmed: 32269076
pii: S0021-9258(17)48201-9
doi: 10.1074/jbc.RA119.011932
pmc: PMC7242709
doi:
Substances chimiques
Histocompatibility Antigens Class I
0
Lysophospholipids
0
Peptides
0
nef Gene Products, Human Immunodeficiency Virus
0
nef protein, Human immunodeficiency virus 1
0
Banques de données
PDB
['4ZFZ']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6983-6991Informations de copyright
© 2020 Shima et al.
Références
Nat Commun. 2016 Jan 13;7:10356
pubmed: 26758274
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):235-42
pubmed: 21460441
Nat Rev Immunol. 2011 Nov 11;11(12):823-36
pubmed: 22076556
J Virol. 2013 Jan;87(1):482-8
pubmed: 23097434
Nature. 1989 May 18;339(6221):223-6
pubmed: 2785645
J Exp Med. 2014 Jun 30;211(7):1363-77
pubmed: 24935257
J Immunol. 2019 Jun 15;202(12):3349-3358
pubmed: 31043477
Nature. 1987 Apr 30-May 6;326(6116):881-2
pubmed: 2437457
Adv Biol Regul. 2018 Jan;67:212-218
pubmed: 29248300
Nature. 1991 May 23;351(6324):290-6
pubmed: 1709722
J Exp Med. 1994 Jul 1;180(1):407-12
pubmed: 8006598
Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3065-70
pubmed: 9501216
J Exp Med. 1994 Dec 1;180(6):2163-71
pubmed: 7964491
Cell. 1992 Dec 24;71(7):1205-14
pubmed: 1473153
Clin Chem. 2002 Dec;48(12):2217-24
pubmed: 12446479
J Biol Chem. 1994 May 6;269(18):13057-60
pubmed: 8175726
Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):8053-7
pubmed: 8367462
Science. 1992 Aug 14;257(5072):927-34
pubmed: 1323878
Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2339-44
pubmed: 9122196
Methods Enzymol. 1997;276:307-26
pubmed: 27754618
Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19335-40
pubmed: 22087000
Nat Rev Immunol. 2015 Oct;15(10):643-54
pubmed: 26388332
Hum Immunol. 1994 Sep;41(1):61-8
pubmed: 7530699
Nat Rev Immunol. 2005 May;5(5):363-74
pubmed: 15841099
Science. 1993 Aug 6;261(5122):769-71
pubmed: 8342042
Infect Immun. 2013 Jan;81(1):311-6
pubmed: 23132493
EMBO J. 2012 Apr 18;31(8):2047-59
pubmed: 22395072
J Exp Med. 1994 Jan 1;179(1):335-40
pubmed: 8270878
J Biol Chem. 2016 May 13;291(20):10677-83
pubmed: 27006394
J Biol Chem. 2008 Mar 7;283(10):6428-37
pubmed: 18165686
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501
pubmed: 20383002
PLoS One. 2009;4(5):e5325
pubmed: 19415116
Nat Commun. 2014 Sep 26;5:4919
pubmed: 25255805
Nature. 2016 Jan 28;529(7587):537-40
pubmed: 26789246
Acta Crystallogr D Biol Crystallogr. 2012 Apr;68(Pt 4):352-67
pubmed: 22505256
J Immunol. 1980 Aug;125(2):508-17
pubmed: 7391566
Trends Cell Biol. 2012 Feb;22(2):116-24
pubmed: 22130221
J Mol Biol. 1991 May 20;219(2):277-319
pubmed: 2038058
Nucleic Acids Res. 2007 Jan;35(Database issue):D527-32
pubmed: 17098933
Immunology. 2016 Oct;149(2):139-45
pubmed: 27402593
FEBS J. 2008 Apr;275(8):1915-24
pubmed: 18336573
J Chem Ecol. 2007 Jul;33(7):1376-81
pubmed: 17566833
Nat Immunol. 2015 Mar;16(3):258-66
pubmed: 25642819
J Immunol. 2011 Jul 15;187(2):608-12
pubmed: 21653836