Naturally occurring cell-adapted classic strain of infectious bursal disease virus.

Adaptation, Biological Amino Acid Substitution Animals Birnaviridae Infections / veterinary Cell Culture Techniques Cell Line Chickens / virology China Fibroblasts / virology Genome, Viral Genotype Infectious bursal disease virus / genetics Phylogeny Poultry Diseases / virology Viral Tropism Virulence
Cell-tropism Classic strain Infectious bursal disease virus

Journal

Veterinary microbiology
ISSN: 1873-2542
Titre abrégé: Vet Microbiol
Pays: Netherlands
ID NLM: 7705469

Informations de publication

Date de publication:
Apr 2020
Historique:
received: 29 10 2019
revised: 24 02 2020
accepted: 24 02 2020
entrez: 11 4 2020
pubmed: 11 4 2020
medline: 25 11 2020
Statut: ppublish

Résumé

Infectious bursal disease virus (IBDV), the etiological agent of infectious bursal disease (IBD), is a variable RNA virus of Avibirnavirus. Some artificially attenuated vaccine strains of IBDV can adapt to cell culture of chicken embryo fibroblast (CEF) cell or its immortalized cell line DF1 in vitro while wild-type IBDV cannot. In this study, for the first time, a naturally occurring cell-adapted classic strain (genogroup 1) of IBDV named IBD17JL01 was identified in China. Animal experiments showed that IBD17JL01 could severely damage the central immune organ of infected chickens. Sequence analysis of the full-length genome revealed the peculiar molecular characteristics of IBD17JL01 with a few amino acid substitutions that might be involved in cell-tropism, antigenicity, and virulence of IBDV. Identification of this novel strain is beneficial to our understanding of the complexity of the epidemiology of IBDV. And the expansion of viral cell-tropism might increase the potential risk of the reassortment of different IBDVs including the live vaccines.

Identifiants

DOI: 10.1016/j.vetmic.2020.108620 PMID: 32273006
pubmed: 32273006
pii: S0378-1135(19)31273-8
doi: 10.1016/j.vetmic.2020.108620
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108620

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no competing interests.

Auteurs

Yulong Wang (Y)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China; OIE Reference Laboratory for Infectious Bursal Disease, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China.

Linjin Fan (L)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China; OIE Reference Laboratory for Infectious Bursal Disease, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China.

Nan Jiang (N)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China; OIE Reference Laboratory for Infectious Bursal Disease, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China.

Li Gao (L)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China; OIE Reference Laboratory for Infectious Bursal Disease, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China.

Kai Li (K)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China; OIE Reference Laboratory for Infectious Bursal Disease, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China.

Yulong Gao (Y)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China; OIE Reference Laboratory for Infectious Bursal Disease, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China.

Changjun Liu (C)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China.

Hongyu Cui (H)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China.

Qing Pan (Q)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China.

Yanping Zhang (Y)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China.

Xiaomei Wang (X)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China; OIE Reference Laboratory for Infectious Bursal Disease, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou 225009, PR China.

Xiaole Qi (X)

Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China; OIE Reference Laboratory for Infectious Bursal Disease, Harbin Veterinary Research Institute, the Chinese Academy of Agricultural Sciences, Harbin 150069, PR China. Electronic address: qixiaole@caas.cn.

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Classifications MeSH

questionsmedicales.fr › Phénomènes biologiques › Adaptation biologique › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Phénomènes génétiques › Mutagenèse › Substitution d'acide aminé › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Eucaryotes › Animaux › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Infection › Maladies virales › Infections à virus à ARN › Infections à Birnaviridae › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Techniques d'investigation › Techniques in vitro › Techniques de culture › Techniques de culture cellulaire › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Oiseaux › Poulets › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Régions géographiques › Asie › Extrême-Orient › Chine › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Fibroblastes › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Génome microbien › Génome viral › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN double brin › Birnaviridae › Avibirnavirus › Virus de la bursite infectieuse › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Sciences de l'information › Phylogenèse › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Maladies de l'animal › Maladies des oiseaux › Maladies de la volaille › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques viraux › Tropisme viral › Naturally occurring cell-adapted classic...
questionsmedicales.fr › Phénomènes microbiologiques › Virulence › Naturally occurring cell-adapted classic...