Comparison of dimethylated and methylchlorinated amylose stationary phases, coated and covalently immobilized on silica, for the separation of some chiral compounds in supercritical fluid chromatography.
1-aryl-5-aryl-pyrrolidin-2-ones
Amylose tris(3,5-dimethylphenylcarbamate)
Amylose tris(3-chloro-5-methylphenylcarbamate)
Amylose tris(5-chloro-2-methylphenylcarbamate)
Chirality
Journal
Journal of chromatography. A
ISSN: 1873-3778
Titre abrégé: J Chromatogr A
Pays: Netherlands
ID NLM: 9318488
Informations de publication
Date de publication:
21 Jun 2020
21 Jun 2020
Historique:
received:
26
12
2019
revised:
05
03
2020
accepted:
16
03
2020
pubmed:
12
4
2020
medline:
22
7
2020
entrez:
12
4
2020
Statut:
ppublish
Résumé
The chromatographic properties of a new coated amylose tris(3-chloro-5-methylphenylcarbamate) were evaluated in supercritical fluid chromatography for the separation of enantiomers of chiral 1-aryl-5-aryl-pyrrolidin-2-one derivatives, potential anticancer agents, and some commercial drugs. The mobile phase consisted of CO
Identifiants
pubmed: 32276857
pii: S0021-9673(20)30265-X
doi: 10.1016/j.chroma.2020.461053
pii:
doi:
Substances chimiques
Antineoplastic Agents
0
Carbamates
0
Pharmaceutical Preparations
0
Phenylcarbamates
0
Pyrrolidinones
0
amylose tris(3-chloro-5-methylphenylcarbamate)
0
amylose-tris-(5-chloro-2-methylphenylcarbamate)
0
Chiralpak AD
138361-09-8
Silicon Dioxide
7631-86-9
Amylose
9005-82-7
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
461053Informations de copyright
Copyright © 2020. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.